Literature DB >> 4119224

Immunochemical analysis of the cross-reacting idiotypes of mouse myeloma proteins with anti-dextran activity and normal anti-dextran antibody.

D Carson, M Weigert.   

Abstract

The idiotype of the mouse myeloma protein with anti-alpha-1,3 dextran activity, J558, has been characterized by a solid-phase radioimmunoassay. The idiotype of the J558 protein depends on a specific light and heavy chain interaction and is altered in the presence of the hapten, nigerose. Cross-reacting idiotypes were found on another mouse myeloma protein with alpha1,3 dextran specificity, normal anti-dextran antibody, and certain reconstructed myeloma proteins composed of the J558 heavy chain and heterologous light chains.

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Year:  1973        PMID： 4119224      PMCID： PMC433222          DOI： 10.1073/pnas.70.1.235

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  17 in total

1.  Heterogeneity in dextran preparations.

Authors:  C A WILHAM; B H ALEXANDER; A JEANES
Journal:  Arch Biochem Biophys       Date:  1955-11       Impact factor: 4.013

2.  Solid phase radioimmunoassay of human beta 1C globulin.

Authors:  P W Askenase; E J Leonard
Journal:  Immunochemistry       Date:  1970-01

Review 3.  Genetics of immunoglobulins in the mouse.

Authors:  M Potter; R Lieberman
Journal:  Adv Immunol       Date:  1967       Impact factor: 3.543

4.  The use of affinity chromatography for the specific purification of antibodies and antigens.

Authors:  L Wofsy; B Burr
Journal:  J Immunol       Date:  1969-08       Impact factor: 5.422

5.  Immunochemical studies on mouse myeloma proteins with specificity for dextran or for levan.

Authors:  A Lundblad; R Steller; E A Kabat; J W Hirst; M G Weigert; M Cohn
Journal:  Immunochemistry       Date:  1972-05

6.  Variability in the lambda light chain sequences of mouse antibody.

Authors:  M G Weigert; I M Cesari; S J Yonkovich; M Cohn
Journal:  Nature       Date:  1970-12-12       Impact factor: 49.962

7.  Experimental approaches tohomogenous antibody populations. iIndividual antigenic specificity, cross specificity and diversity of human antibodies.

Authors:  H G Kunkel
Journal:  Fed Proc       Date:  1970 Jan-Feb

8.  Genetics of the antibody response to dextran in mice.

Authors:  B Blomberg; W R Geckeler; M Weigert
Journal:  Science       Date:  1972-07-14       Impact factor: 47.728

9.  A genetic marker in the variable region of light chains of mouse immunoglobulins.

Authors:  G M Edelman; P D Gottlieb
Journal:  Proc Natl Acad Sci U S A       Date:  1970-11       Impact factor: 11.205

10.  Quantitative investigations of idiotypic antibodies. IV. Inhibition by specific haptens of the reaction of anti-hapten antibody with its anti-idiotypic antibody.

Authors:  B W Brient; A Nisonoff
Journal:  J Exp Med       Date:  1970-11       Impact factor: 14.307
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  39 in total

1.  Limiting CDR-H3 diversity abrogates the antibody response to the bacterial polysaccharide α 1→3 dextran.

Authors:  Tamer I Mahmoud; Harry W Schroeder; John F Kearney
Journal:  J Immunol       Date:  2011-06-15       Impact factor: 5.422

2.  Segregation at a locus determining an immunoglobulin genetic marker for the light chain variable region affects inheritance of expression of an idiotype.

Authors:  J A Laskin; A Gray; A Nisonoff; N R Klinman; P D Gottlieb
Journal:  Proc Natl Acad Sci U S A       Date:  1977-10       Impact factor: 11.205

3.  Cross idiotypic specificity among cold agglutinins in relation to combining activity for blood group-related antigens.

Authors:  T Feizi; H G Kunkel; D Roelcke
Journal:  Clin Exp Immunol       Date:  1974-10       Impact factor: 4.330

4.  Three-dimensional structure of the Fab' fragment of a human immunoglobulin at 2,8-A resolution.

Authors:  R J Poljak; L M Amzel; H P Avey; B L Chen; R P Phizackerley; F Saul
Journal:  Proc Natl Acad Sci U S A       Date:  1973-12       Impact factor: 11.205

Review 5.  The polyclonal expression of immunoglobulin variable region determinants on the membrane of B cells and their precursors.

Authors:  A Coutinho; L Forni; R R Bernabé
Journal:  Springer Semin Immunopathol       Date:  1980-08

Review 6.  Autoregulation of immune responses via idiotype network interactions.

Authors:  L S Rodkey
Journal:  Microbiol Rev       Date:  1980-12

7.  A common idiotype on human macroglobulins with anti-I and anti-i specificity.

Authors:  J Lecomte; T Feizi
Journal:  Clin Exp Immunol       Date:  1975-05       Impact factor: 4.330

8.  Demonstration of anti-idiotypic antibodies directed against IgM rheumatoid factor in the serum of rheumatoid arthritis patients.

Authors:  W K Hancock; E V Barnett
Journal:  Clin Exp Immunol       Date:  1989-01       Impact factor: 4.330

9.  Terminal deoxynucleotidyl transferase is required for an optimal response to the polysaccharide α-1,3 dextran.

Authors:  Tamer I Mahmoud; John F Kearney
Journal:  J Immunol       Date:  2009-12-16       Impact factor: 5.422

10.  Human and murine phosphorycholine-binding immunoglobulins: conserved subgroup and first hypervariable region of heavy chains.

Authors:  W F Riesen; D G Braun; J C Jaton
Journal:  Proc Natl Acad Sci U S A       Date:  1976-06       Impact factor: 11.205
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