Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 The radioimmunoassay of circulating carcinoembryonic antigen of the human digestive system.

Literature DB >> 5262998

The radioimmunoassay of circulating carcinoembryonic antigen of the human digestive system.

D M Thomson, J Krupey, S O Freedman, P Gold.

Abstract

A radioimmunoassay has been developed for determining the serum levels of carcinoembryonic antigen of the human digestive system in patients with cancer of the colon and rectum. The assay is simple to perform and has a high degree of reproducibility and specificity. The test detects a concentration of 2.5 ng of carcinoembryonic antigen per ml of serum and this has provided the first demonstration of a circulating tumor-specific antigen in the sera of cancer patients.

Entities: Disease Species

Mesh：

Substances：

Year: 1969 PMID： 5262998 PMCID： PMC286141 DOI： 10.1073/pnas.64.1.161

Source DB: PubMed Journal: Proc Natl Acad Sci U S A ISSN： 0027-8424 Impact factor: 11.205

7 in total

1. Immunoassay of endogenous plasma insulin in man.

Authors: R S YALOW; S A BERSON
Journal: J Clin Invest Date: 1960-07 Impact factor: 14.808

2. A quantitative immunochemical measure of the primary interaction between I BSA and antibody.

Authors: R S FARR
Journal: J Infect Dis Date: 1958 Nov-Dec Impact factor: 5.226

3. Cellular location of carcinoembryonic antigens of the human digestive system.

Authors: P Gold; M Gold; S O Freedman
Journal: Cancer Res Date: 1968-07 Impact factor: 12.701

4. A radio-immunoelectrophoretic assay for human growth hormone.

Authors: W M Hunter; F C Greenwood
Journal: Biochem J Date: 1964-04 Impact factor: 3.857

5. DEMONSTRATION OF TUMOR-SPECIFIC ANTIGENS IN HUMAN COLONIC CARCINOMATA BY IMMUNOLOGICAL TOLERANCE AND ABSORPTION TECHNIQUES.

Authors: P GOLD; S O FREEDMAN
Journal: J Exp Med Date: 1965-03-01 Impact factor: 14.307

6. Physicochemical studies of the carcinoembryonic antigens of the human digestive system.

Authors: J Krupey; P Gold; S O Freedman
Journal: J Exp Med Date: 1968-09-01 Impact factor: 14.307

7. Specific carcinoembryonic antigens of the human digestive system.

Authors: P Gold; S O Freedman
Journal: J Exp Med Date: 1965-09-01 Impact factor: 14.307

7 in total

128 in total

1. Identification of phospholipid scramblase 1 as a biomarker and determination of its prognostic value for colorectal cancer.

Authors: Yung-Bin Kuo; Chung-Chuan Chan; C Allen Chang; Chung-Wei Fan; Ray-Ping Hung; Ya-Shu Hung; Kuei-Tien Chen; Jau-Song Yu; Yu-Sun Chang; Err-Cheng Chan
Journal: Mol Med Date: 2010-10-05 Impact factor: 6.354

8. Target mediated disposition of T84.66, a monoclonal anti-CEA antibody: application in the detection of colorectal cancer xenografts.

Authors: Shweta R Urva; Joseph P Balthasar
Journal: MAbs Date: 2010-01-26 Impact factor: 5.857

9. The prognostic significance of preoperative carcinoembryonic antigen levels in colorectal cancer. Results from NSABP (National Surgical Adjuvant Breast and Bowel Project) clinical trials.

Authors: N Wolmark; B Fisher; H S Wieand; R S Henry; H Lerner; S Legault-Poisson; P J Deckers; N Dimitrov; P H Gordon; P Jochimsen
Journal: Ann Surg Date: 1984-04 Impact factor: 12.969

10. Roôle of carcinoembryonic antigen in bronchial carcinoma.

Authors: C H Ford; C E Newman; J Lakin
Journal: Thorax Date: 1977-10 Impact factor: 9.139

The radioimmunoassay of circulating carcinoembryonic antigen of the human digestive system.

1. Immunoassay of endogenous plasma insulin in man.

2. A quantitative immunochemical measure of the primary interaction between I BSA and antibody.

3. Cellular location of carcinoembryonic antigens of the human digestive system.

4. A radio-immunoelectrophoretic assay for human growth hormone.

5. DEMONSTRATION OF TUMOR-SPECIFIC ANTIGENS IN HUMAN COLONIC CARCINOMATA BY IMMUNOLOGICAL TOLERANCE AND ABSORPTION TECHNIQUES.

6. Physicochemical studies of the carcinoembryonic antigens of the human digestive system.

7. Specific carcinoembryonic antigens of the human digestive system.

1. Identification of phospholipid scramblase 1 as a biomarker and determination of its prognostic value for colorectal cancer.

2. Carcinoembryonic antigen in patients suffering from ulcerative proctocolitis.

3. Early detection and mass screening for cancer.

4. A technical improvement in the radioimmunoassay of cyclic-AMP.

5. Plasma levels of carcinoembryonic antigen in bronchial carcinoma and chronic bronchitis.

6. Carcinoembryonic antigen and prognosis in patients with colon cancer.

7. Serum carcinoembryonic antigen in clinical disorders.

8. Target mediated disposition of T84.66, a monoclonal anti-CEA antibody: application in the detection of colorectal cancer xenografts.

9. The prognostic significance of preoperative carcinoembryonic antigen levels in colorectal cancer. Results from NSABP (National Surgical Adjuvant Breast and Bowel Project) clinical trials.

10. Roôle of carcinoembryonic antigen in bronchial carcinoma.