Literature DB >> 4115520

DNA polymerases from RNA tumor viruses and human cells: inhibition by polyuridylic acid.

J W Abrell, R G Smith, M S Robert, B C Gallo.   

Abstract

Polyuridylic acid inhibited DNA polymerases purified from three species of oncornaviruses as well as three out of seven DNA polymerases purified from cells. Viral and cellular DNA polymerases could not be distinguished by polyuridylic acid inhibition, but were easily distinguished by their template preferences in the presence of magnesium.

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Year:  1972        PMID： 4115520     DOI： 10.1126/science.177.4054.1111

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  6 in total

1.  Effects of polyadenylic acids on functions of murine RNA tumor viruses.

Authors:  R W Tennant; J G Farrelly; J N Ihle; B C Pal; F T Kenney; A Brown
Journal:  J Virol       Date:  1973-12       Impact factor: 5.103

2.  Effects of poly(2'-O-methyladenylic acid) on susceptibility and autogenous immunity to RNA tumor virus oncogenesis in vivo.

Authors:  R W Tennant; M G Hanna; J G Farrelly
Journal:  Proc Natl Acad Sci U S A       Date:  1974-08       Impact factor: 11.205

3.  Reverse transcriptase-associated RNase H activity. II. Inhibition by natural and synthetic RNA.

Authors:  S L Marcus; S W Smith; M J Modak
Journal:  J Virol       Date:  1978-09       Impact factor: 5.103

4.  Inhibition of vesicular stomatitis virus replication by poly(2'-fluoro-2'-deoxyuridylic acid).

Authors:  J C Grosch; R J Erickson
Journal:  Antimicrob Agents Chemother       Date:  1975-11       Impact factor: 5.191

5.  Inhibition of oncornavirus functions by 2'-azido polynucleotides.

Authors:  E De Clercq; A Billiau; J Hobbs; P F Torrence; B Witkop
Journal:  Proc Natl Acad Sci U S A       Date:  1975-01       Impact factor: 11.205

6.  Inhibition of oncornavirus functions by poly (2-methylthioinosinic acid).

Authors:  E De Clercq; A Billiau; M Hattori; M Ikehara
Journal:  Nucleic Acids Res       Date:  1975-12       Impact factor: 16.971
  6 in total

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