| Literature DB >> 4113510 |
Abstract
Specific binding of aggregated gamma-globulin to a subpopulation of lymphocytes was demonstrated. This subpopulation was identified as the Ig-staining or B lymphocytes. The binding was irreversible and independent of complement, pH, temperature, protein content of the medium, and divalent cations. Aggregates of large size were needed for optimal visualization. Evidence was obtained that the site on the lymphocyte membrane responsible for binding aggregates was distinct from surface Ig.Mesh:
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Year: 1972 PMID: 4113510 PMCID: PMC2139185 DOI: 10.1084/jem.136.1.191
Source DB: PubMed Journal: J Exp Med ISSN: 0022-1007 Impact factor: 14.307