Literature DB >> 4109599

Ultrastructure of the human complement component, Clq (negative staining-glutamine synthetase-biologically active Clq).

E Shelton, K Yonemasu, R M Stroud.   

Abstract

The human complement component, Clq, is a fragile molecule of delicate structure consisting of three distinct parts, a central subunit, connecting strands, and terminal subunits. Each terminal subunit is further subdivided into a large and a small subunit, and the central subunit appears to be divided into two equal parts. In the intact molecule, six connecting strands link six terminal subunits by their larger subdivision to the central subunit. The overall diameter of the molecule when viewed from the "top" is about 35 nm (350 A).

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Year:  1972        PMID: 4109599      PMCID: PMC427545          DOI: 10.1073/pnas.69.1.65

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN: 0027-8424            Impact factor:   11.205


  7 in total

1.  Chemical studies of Clq; a modulator of immunoglobulin biology.

Authors:  K Yonemasu; R M Stroud; W Niedermeier; W T Butler
Journal:  Biochem Biophys Res Commun       Date:  1971-06-18       Impact factor: 3.575

Review 2.  Chemistry and reaction mechanisms of complement.

Authors:  H J Müller-Eberhard
Journal:  Adv Immunol       Date:  1968       Impact factor: 3.543

3.  Regulation of glutamine synthetase. XII. Electron microscopy of the enzyme from Escherichia coli.

Authors:  R C Valentine; B M Shapiro; E R Stadtman
Journal:  Biochemistry       Date:  1968-06       Impact factor: 3.162

4.  Ultrastructure of the gamma M immunoglobulin-molecule.

Authors:  E Shelton; K R McIntire
Journal:  J Mol Biol       Date:  1970-02-14       Impact factor: 5.469

5.  Clq: rapid purification method for preparation of monospecific antisera and for biochemical studies.

Authors:  K Yonemasu; R M Stroud
Journal:  J Immunol       Date:  1971-02       Impact factor: 5.422

6.  The ultrastructure of human C1q.

Authors:  S E Svehag; B Bloth
Journal:  Acta Pathol Microbiol Scand B Microbiol Immunol       Date:  1970

7.  The ultrastructure of normal and pathological IgM immunoglobulins.

Authors:  B Chesebro; B Bloth; S E Svehag
Journal:  J Exp Med       Date:  1968-03-01       Impact factor: 14.307

  7 in total
  43 in total

1.  Structural flexibility and functional valence of CD4-IgG2 (PRO 542): potential for cross-linking human immunodeficiency virus type 1 envelope spikes.

Authors:  P Zhu; W C Olson; K H Roux
Journal:  J Virol       Date:  2001-07       Impact factor: 5.103

2.  The oligomeric structure of high molecular weight adiponectin.

Authors:  Shinji Suzuki; Elizabeth M Wilson-Kubalek; David Wert; Tsu-Shuen Tsao; David H Lee
Journal:  FEBS Lett       Date:  2007-01-30       Impact factor: 4.124

3.  Increase of urinary and serum hydroxyproline in subjects exposed to cadmium.

Authors:  H Nishino; T Tanaka; K Shiroishi; S Sato; Y Naruse; S Kagamimori
Journal:  Bull Environ Contam Toxicol       Date:  1991-10       Impact factor: 2.151

4.  Thermodynamics and density of binding of a panel of antibodies to high-molecular-weight capsular polysaccharides.

Authors:  Shannon L Harris; Philip Fernsten
Journal:  Clin Vaccine Immunol       Date:  2008-11-12

5.  Circular-dichroism and electron-microscopy studies of human subcomponent C1q before and after limited proteolysis by pepsin.

Authors:  B Brodsky-Doyle; K R Leonard; K B Reid
Journal:  Biochem J       Date:  1976-11       Impact factor: 3.857

6.  Molecular modelling of human complement subcomponent C1q and its complex with C1r2C1s2 derived from neutron-scattering curves and hydrodynamic properties.

Authors:  S J Perkins
Journal:  Biochem J       Date:  1985-05-15       Impact factor: 3.857

7.  Subunit composition and structure of subcomponent C1q of the first component of human complement.

Authors:  K B Reid; R R Porter
Journal:  Biochem J       Date:  1976-04-01       Impact factor: 3.857

8.  Complete amino acid sequences of the three collagen-like regions present in subcomponent C1q of the first component of human complement.

Authors:  K B Reid
Journal:  Biochem J       Date:  1979-05-01       Impact factor: 3.857

9.  Identification of the Raji cell membrane-derived C1q inhibitor as a receptor for human C1q. Purification and immunochemical characterization.

Authors:  B Ghebrehiwet; L Silvestri; C McDevitt
Journal:  J Exp Med       Date:  1984-11-01       Impact factor: 14.307

10.  Detection of circulating IgG aggregates and immune complexes using 125I protein A from Staphylococcus aureus.

Authors:  R Hällgren; L Wide
Journal:  Ann Rheum Dis       Date:  1976-08       Impact factor: 19.103

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