Literature DB >> 4108501

Amino acid sequence of the encephalitogenic basic protein from human myelin.

P R Carnegie.   

Abstract

Myelin from the central nervous system contains an unusual basic protein, which can induce experimental autoimmune encephalomyelitis. The basic protein from human brain was digested with trypsin and other enzymes and the sequence of the 170 amino acids was determined. The localization of the encephalitogenic determinants was described. Possible roles for the protein in the structure and function of myelin are discussed.

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Year:  1971        PMID： 4108501      PMCID： PMC1176899          DOI： 10.1042/bj1230057

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  38 in total

1.  The action of trypsin on polylysine.

Authors:  S G WALEY; J WATSON
Journal:  Biochem J       Date:  1953-09       Impact factor: 3.857

2.  A simple procedure for the fractionation of the tryptic peptides of the C-terminal half of immunoglobulin lambda-chains.

Authors:  C Milstein
Journal:  Biochem J       Date:  1968-12       Impact factor: 3.857

3.  Amino acid sequence adjoining the lone tryptophan of human serum albumin. A binding site of the protein.

Authors:  J B Swaney; I M Klotz
Journal:  Biochemistry       Date:  1970-06-23       Impact factor: 3.162

4.  The identity of a myelin-like fraction isolated from developing brain.

Authors:  H C Agrawal; N L Banik; A H Bone; A N Davison; R F Mitchell; M Spohn
Journal:  Biochem J       Date:  1970-12       Impact factor: 3.857

5.  Role of a buried acid group in the mechanism of action of chymotrypsin.

Authors:  D M Blow; J J Birktoft; B S Hartley
Journal:  Nature       Date:  1969-01-25       Impact factor: 49.962

6.  Digestion of an arg-pro bond by trypsin in the ecephalitogenic basic protein of human myelin.

Authors:  P R Carnegie
Journal:  Nature       Date:  1969-08-30       Impact factor: 49.962

7.  Experimental autoimmune encephalomyelitis. Digestion of basic protein of human myelin with cyanogen bromide and trypsin.

Authors:  P R Carnegie; T A McPherson; G S Robson
Journal:  Immunology       Date:  1970-07       Impact factor: 7.397

8.  The structure of the terminal regions of the encephalitogenic basic protein from bovine myelin.

Authors:  G A Hashim; E H Eylar
Journal:  Arch Biochem Biophys       Date:  1969-12       Impact factor: 4.013

9.  Encephalitogenic protein: structure.

Authors:  R F Kibler; R Shapira; S McKneally; J Jenkins; P Selden; F Chou
Journal:  Science       Date:  1969-05-02       Impact factor: 47.728

10.  Isolation and partial characterization of methylated arginines from the encephalitogenic basic protein of myelin.

Authors:  G S Baldwin; P R Carnegie
Journal:  Biochem J       Date:  1971-06       Impact factor: 3.857
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  37 in total

1.  Myelin and myelinization in the telencephalon and mesencephalon of the lizard Gallotia galloti as revealed by the immunohistochemical localization of myelin basic protein.

Authors:  C Yanes; M Monzon-Mayor; J de Barry; G Gombos
Journal:  Anat Embryol (Berl)       Date:  1992

2.  The role of proteolytic enzymes in demyelination in experimental allergic encephalomyelitis.

Authors:  M E Smith
Journal:  Neurochem Res       Date:  1977-06       Impact factor: 3.996

3.  Dipeptide frequencies in proteins and the CpG deficiency in vertebrate DNA.

Authors:  E Bullock; R A Elton
Journal:  J Mol Evol       Date:  1972-12       Impact factor: 2.395

4.  Identification of three forms of human myelin basic protein by cDNA cloning.

Authors:  J Kamholz; F de Ferra; C Puckett; R Lazzarini
Journal:  Proc Natl Acad Sci U S A       Date:  1986-07       Impact factor: 11.205

5.  Soluble bovine galactose-binding lectin. cDNA cloning reveals the complete amino acid sequence and an antigenic relationship with the major encephalitogenic domain of myelin basic protein.

Authors:  W M Abbott; A Mellor; Y Edwards; T Feizi
Journal:  Biochem J       Date:  1989-04-01       Impact factor: 3.857

6.  Fine specificity of the antibody response to myelin basic protein in the central nervous system in multiple sclerosis: the minimal B-cell epitope and a model of its features.

Authors:  K G Warren; I Catz; L Steinman
Journal:  Proc Natl Acad Sci U S A       Date:  1995-11-21       Impact factor: 11.205

7.  Detection of various forms of brain myelin basic protein in vertebrates by electroimmunoblotting.

Authors:  N Kerlero De Rosbo; P R Carnegie; C C Bernard; D S Linthicum
Journal:  Neurochem Res       Date:  1984-10       Impact factor: 3.996

8.  Endogenous cyclic AMP-stimulated phosphorylation of a Wolfgram protein component in rabbit central-nervous-system myelin.

Authors:  J M Bradbury; R S Campbell; R J Thompson
Journal:  Biochem J       Date:  1984-07-15       Impact factor: 3.857

9.  Phylogenetically conserved amino acids of MBP and P0 from amphibian myelin.

Authors:  J Karthigasan; T K Bauer; D B Teplow; R A Saavedra; D A Kirschner
Journal:  J Mol Neurosci       Date:  1992       Impact factor: 3.444

10.  Antigen specificity of clonally expanded and receptor edited cerebrospinal fluid B cells from patients with relapsing remitting MS.

Authors:  Doris Lambracht-Washington; Kevin C O'Connor; Elizabeth M Cameron; Andrea Jowdry; E Sally Ward; Elliot Frohman; Michael K Racke; Nancy L Monson
Journal:  J Neuroimmunol       Date:  2007-04-23       Impact factor: 3.478
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