Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Interaction between prostaglandins E and F given intradermally in the rat.

Literature DB >> 4102679

Interaction between prostaglandins E and F given intradermally in the rat.

Abstract

1. Increases in permeability observed after intradermal injection of prostaglandins PGE(1) or PGE(2) (0.1 mug) into rats were greatly reduced when they were given in admixture with PGF(2alpha). This effect was not seen with PGF(1alpha) at doses of 0.5-1 mug.2. Effects of the histamine releasing agent compound 48/80 (25 ng) were inhibited by PGF(2alpha) (0.5 mug) but not by PGF(1alpha) (0.5 mug).3. Responses to histamine (1 mug), 5-hydroxytryptamine (0.1 mug) and bradykinin (1 mug), which have a direct action on the microvasculature, were not significantly altered by PGF(2alpha) (0.5 mug).4. It is concluded that PGF(2alpha) probably acts by interfering with the release of mast cell histamine by PGE(1), PGE(2) and compound 48/80.

Entities: Chemical Species

Mesh：

Substances：

Year: 1971 PMID： 4102679 PMCID： PMC1702861 DOI： 10.1111/j.1476-5381.1971.tb08048.x

Source DB: PubMed Journal: Br J Pharmacol ISSN： 0007-1188 Impact factor: 8.739

11 in total

1. Proceedings: Prostaglandin D1 inhibits the increase in vascular permeability in rat skin produced by prostaglandin E1, E2 and D2.

Authors: R J Flower; W P Kingston
Journal: Br J Pharmacol Date: 1975-10 Impact factor: 8.739

2. Anti-inflammatory action of corticosteroids.

Authors: M W Greaves
Journal: Postgrad Med J Date: 1976-10 Impact factor: 2.401

3. Proceedings: The determination of the fatty acid profile of lecithin from human amniotic fluid and the pharyngeal aspirate of the new-born.

Authors: C M Hill
Journal: J Physiol Date: 1976-05 Impact factor: 5.182

Interaction between prostaglandins E and F given intradermally in the rat.

1. EFFECT OF MECHANICAL STIMULATION ON RABBITS' EYES: RELEASE OF ACTIVE SUBSTANCE IN ANTERIOR CHAMBER PERFUSATES.

2. THE BIOSYNTHESIS OF PROSTAGLANDIN E1 STUDIED WITH SPECIFICALLY 3H-LABELLED 8,11,14-EICOSATRIENOIC ACIDS.

3. THE ORIGIN OF OXYGEN INCORPORATED DURING THE BIOSYNTHESIS OF PROSTAGLANDIN E-1.

4. Further studies on the preparation, purification and nature of irin.

5. Prostaglandin release from and formation in perfused frog intestine.

Review 6. The prostaglandins: a family of biologically active lipids.

7. Actions and interactions of prostaglandins administered intradermally in rat and in man.

8. The participation of molecular oxygen in the biosynthesis of prostaglandins.

9. On the mechanism of the biosynthesis of prostaglandins E-1 and F-1-alpha.

10. Cutaneous reactions to intradermal prostaglandins.

1. Proceedings: Prostaglandin D1 inhibits the increase in vascular permeability in rat skin produced by prostaglandin E1, E2 and D2.

2. Anti-inflammatory action of corticosteroids.

3. Proceedings: The determination of the fatty acid profile of lecithin from human amniotic fluid and the pharyngeal aspirate of the new-born.

4. Prostaglandins in pyometrial fluid from the cow, bitch and ferret.

Review 5. The role of prostaglandins in inflammation.

Review 6. Regulation of lysosomal enzyme secretion: role in inflammation.

7. Mechanisms of delayed red cell destruction after thermal injury. An experimental in vitro sem study.

8. The role of prostaglandins in inflammatory reactions.

9. Prostaglandin E2, prostaglandin I2 and the vascular changes of inflammation.

10. Release of prostaglandins from human polymorphonuclear leukocytes.