Literature DB >> 41019

Slow reacting substance (SRS) from ionophore A23187-stimulated human leukemic basophils. I. Evidence for a precursor role of arachidonic acid and initial purification.

L D Yecies, H J Wedner, C W Parker.   

Abstract

SRS was generated from human leukemic basophils upon stimulation with ionophore A23187. Radiolabel from [14C]-AA was incorporated into SRS with continued comigration of radioactivity and bioactivity through several chromatographic systems including DEAE-cellulose, silicic acid, and RP-HPLC. Human basophilic leukemia SRS displayed physiochemical properties similar to those of rat basophilic leukemia cell SRS.

Entities:  

Mesh：

Substances：

Year:  1979        PMID： 41019

Source DB:  PubMed          Journal:  J Immunol        ISSN： 0022-1767            Impact factor:   5.422


  4 in total

Review 1.  Enzyme mediators of mast cells and basophils.

Authors:  L B Schwartz
Journal:  Clin Rev Allergy       Date:  1983-09

2.  Release of a slow-reacting substance from rabbit platelets.

Authors:  J M Mencia-Huerta; L Hadji; J Benveniste
Journal:  J Clin Invest       Date:  1981-12       Impact factor: 14.808

3.  SRS-A mediated bronchospasm by pharmacologic modification of lung anaphylaxis in vivo.

Authors:  D M Ritchie; J N Sierchio; R J Capetola; M E Rosenthale
Journal:  Agents Actions       Date:  1981-07

4.  Release of leukotrienes C (LTC) and D (LTD) from inflammatory macrophages during phagocytosis of zymosan and bacteria.

Authors:  R Roubin; J Benveniste
Journal:  Agents Actions       Date:  1981-12
  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.