Literature DB >> 4099030

Hybrid cell line from a cloned immunoglobulin-producing mouse myeloma and a nonproducing mouse lymphoma.

B Mohit, K Fan.   

Abstract

A hybrid cell line was established by cell fusion between a cloned Balbic myeloma that is resistant to 8-azaguanine and produces immunoglobulin (gammaG and free kappa chain) and C57BL/6N lymphoma that is resistant to bromo-deoxyuridine and does not produce immunoglobulins. The hybrid cells contained the membrane antigens of both parents; they synthesized free kappa chain; no synthesis of gammaG (gamma(2a)) heavy chain was detected.

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Year:  1971        PMID： 4099030     DOI： 10.1126/science.171.3966.75

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  22 in total

1.  Helix-loop-helix transcriptional activators bind to a sequence in glucocorticoid response elements of retrovirus enhancers.

Authors:  B Corneliussen; A Thornell; B Hallberg; T Grundström
Journal:  J Virol       Date:  1991-11       Impact factor: 5.103

2.  Binding of SL3-3 enhancer factor 1 transcriptional activators to viral and chromosomal enhancer sequences.

Authors:  A Thornell; B Hallberg; T Grundström
Journal:  J Virol       Date:  1991-01       Impact factor: 5.103

3.  Mutant analysis of protein interactions with a nuclear factor I binding site in the SL3-3 virus enhancer.

Authors:  P Nilsson; B Hallberg; A Thornell; T Grundström
Journal:  Nucleic Acids Res       Date:  1989-06-12       Impact factor: 16.971

4.  Theta antigen and immunogolbulin on a tissue-cultured mouse lymphoma.

Authors:  A W Boylston
Journal:  Immunology       Date:  1973-05       Impact factor: 7.397

Review 5.  Use of somatic cell hybrids for analysis of the differentiated state.

Authors:  F M Davis; E A Adelberg
Journal:  Bacteriol Rev       Date:  1973-06

Review 6.  Utilization of somatic cell hybrids for genetic studies in man.

Authors:  K H Grzeschik
Journal:  Humangenetik       Date:  1973

7.  Glucocorticoid action on hybrid clones derived from cultured myeloma and lymphoma cell lines.

Authors:  U Gehring; B Mohit; G M Tomkins
Journal:  Proc Natl Acad Sci U S A       Date:  1972-11       Impact factor: 11.205

8.  Transient inhibition of polyoma virus synthesis by Sendai virus (parainfluenza I). I. Demonstration and nature of the inhibition by inactivated virus.

Authors:  G L Smith; R A Consigli
Journal:  J Virol       Date:  1972-12       Impact factor: 5.103

9.  Expression of differentiated functions in hepatoma cell hybrids: induction of mouse albumin production in rat hepatoma-mouse fibroblast hybrids.

Authors:  J A Peterson; M C Weiss
Journal:  Proc Natl Acad Sci U S A       Date:  1972-03       Impact factor: 11.205

10.  Induction of amplified synthesis and secretion of IgM by fusion of murine 'b lymphoma with myeloma cells.

Authors:  R Laskov; K J Kim; R Asofsky
Journal:  Proc Natl Acad Sci U S A       Date:  1979-02       Impact factor: 11.205
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