Literature DB >> 4082924

A quantitative and ultrastructural study of substantia nigra and nucleus centralis superior in Alzheimer's disease.

M Tabaton, A Schenone, P Romagnoli, G L Mancardi.   

Abstract

In four patients with presenile Alzheimer's disease (AD) and three age-matched controls a quantitative study of neurons and neurofibrillary tangles (NFT) in the substantia nigra (SN) and nucleus centralis superior (NCS) was performed. A significant neuronal loss, similar in both nuclei, was found in AD cases, while the incidence of NFT was remarkably higher in NCS. Moreover, no significant correlation between neuronal loss and number of NFT was detected. An electron-microscopic study revealed that the subcortical NFT in NCS are made up of paired helical filaments in spite of their globose round shape.

Entities:  

Mesh：

Year:  1985        PMID： 4082924     DOI： 10.1007/BF00690198

Source DB:  PubMed          Journal:  Acta Neuropathol        ISSN： 0001-6322            Impact factor:   17.088


  27 in total

1.  PROGRESSIVE SUPRANUCLEAR PALSY. A HETEROGENEOUS DEGENERATION INVOLVING THE BRAIN STEM, BASAL GANGLIA AND CEREBELLUM WITH VERTICAL GAZE AND PSEUDOBULBAR PALSY, NUCHAL DYSTONIA AND DEMENTIA.

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Journal:  Lancet       Date:  1984-02-04       Impact factor: 79.321

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Journal:  Rinsho Shinkeigaku       Date:  1982-09

5.  Selective loss of central cholinergic neurons in Alzheimer's disease.

Authors:  P Davies; A J Maloney
Journal:  Lancet       Date:  1976-12-25       Impact factor: 79.321

6.  The olfactory bulbs in Alzheimer's disease.

Authors:  M M Esiri; G K Wilcock
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7.  Serotonin nerve cells in Alzheimer's disease.

Authors:  D M Mann; P O Yates
Journal:  J Neurol Neurosurg Psychiatry       Date:  1983-01       Impact factor: 10.154

8.  Alzheimer disease: evidence for selective loss of cholinergic neurons in the nucleus basalis.

Authors:  P J Whitehouse; D L Price; A W Clark; J T Coyle; M R DeLong
Journal:  Ann Neurol       Date:  1981-08       Impact factor: 10.422

9.  The fine structure of subcortical neurofibrillary tangles in progressive supranuclear palsy.

Authors:  O Bugiani; G L Mancardi; A Brusa; A Ederli
Journal:  Acta Neuropathol       Date:  1979-02-15       Impact factor: 17.088

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Authors:  R Y Moore; A E Halaris; B E Jones
Journal:  J Comp Neurol       Date:  1978-08-01       Impact factor: 3.215
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  11 in total

1.  Selective loss of nigral neurons in Alzheimer's disease: a morphometric study.

Authors:  T Uchihara; H Kondo; K Kosaka; H Tsukagoshi
Journal:  Acta Neuropathol       Date:  1992       Impact factor: 17.088

2.  Selective loss of nigral neurons in Pick's disease: a morphometric study.

Authors:  T Uchihara; K Tsuchiya; K Kosaka
Journal:  Acta Neuropathol       Date:  1990       Impact factor: 17.088

Review 3.  Turning on the Light Within: Subcortical Nuclei of the Isodentritic Core and their Role in Alzheimer's Disease Pathogenesis.

Authors:  Panos Theofilas; Sara Dunlop; Helmut Heinsen; Lea Tenenholz Grinberg
Journal:  J Alzheimers Dis       Date:  2015       Impact factor: 4.472

4.  Neuronal cell loss in the dorsal raphe nucleus and the superior central nucleus in myotonic dystrophy: a clinicopathological correlation.

Authors:  S Ono; F Kanda; K Takahashi; Y Fukuoka; K Jinnai; H Kurisaki; S Mitake; T Inagaki; K Nagao
Journal:  Acta Neuropathol       Date:  1995       Impact factor: 17.088

5.  Alzheimer-type pathology in melanin-bleached sections of substantia nigra.

Authors:  T Uchihara; H Kondo; K Ikeda; K Kosaka
Journal:  J Neurol       Date:  1995-08       Impact factor: 4.849

6.  The substantia nigra and ventral tegmental area in Alzheimer's disease and Down's syndrome.

Authors:  W R Gibb; C Q Mountjoy; D M Mann; A J Lees
Journal:  J Neurol Neurosurg Psychiatry       Date:  1989-02       Impact factor: 10.154

7.  Brain stem serotonin-synthesizing neurons in Alzheimer's disease: a clinicopathological correlation.

Authors:  G M Halliday; H L McCann; R Pamphlett; W S Brooks; H Creasey; E McCusker; R G Cotton; G A Broe; C G Harper
Journal:  Acta Neuropathol       Date:  1992       Impact factor: 17.088

8.  Progressive supranuclear palsy: extensive neuropil threads in addition to neurofibrillary tangles. Very similar antigenicity of subcortical neuronal pathology in progressive supranuclear palsy and Alzheimer's disease.

Authors:  A Probst; D Langui; C Lautenschlager; J Ulrich; J P Brion; B H Anderton
Journal:  Acta Neuropathol       Date:  1988       Impact factor: 17.088

9.  The differential involvement of subcortical nuclei in senile dementia of Alzheimer's type.

Authors:  G K Wilcock; M M Esiri; D M Bowen; A O Hughes
Journal:  J Neurol Neurosurg Psychiatry       Date:  1988-06       Impact factor: 10.154

10.  Translocator protein in late stage Alzheimer's disease and Dementia with Lewy bodies brains.

Authors:  Jinbin Xu; Jianjun Sun; Richard J Perrin; Robert H Mach; Kelly R Bales; John C Morris; Tammie L S Benzinger; David M Holtzman
Journal:  Ann Clin Transl Neurol       Date:  2019-07-09       Impact factor: 4.511
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