| Literature DB >> 7283399 |
P J Whitehouse, D L Price, A W Clark, J T Coyle, M R DeLong.
Abstract
The nucleus basalis of Meynert provides diffuse cholinergic input to the neocortex. When compared with an age- and sex-matched control, the nucleus basalis from a patient with Alzheimer disease demonstrated substantial reduction of neurons. Loss of this neuronal population may represent an anatomical correlate of the well-documented cholinergic derangement in Alzheimer disease.Entities:
Mesh：
Year: 1981 PMID： 7283399 DOI： 10.1002/ana.410100203
Source DB: PubMed Journal: Ann Neurol ISSN： 0364-5134 Impact factor: 10.422