Literature DB >> 4077731

Physico-chemical and biological properties of actagardine and some acid hydrolysis products.

A Malabarba, M Landi, R Pallanza, B Cavalleri.   

Abstract

Actagardine (originally designated as metabolite B or gardimycin) is a polypeptide antibiotic produced by fermentation of Actinoplanes strains ATCC 31048 and 31049. During the course of repeated fermentations two new compounds, coded D and E, were isolated. Some physico-chemical and biological characteristics of actagardine and of both compounds are presented. Compound D is derived from chemical transformation of actagardine.

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Year:  1985        PMID: 4077731     DOI: 10.7164/antibiotics.38.1506

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN: 0021-8820            Impact factor:   2.649


  2 in total

Review 1.  New horizons for host defense peptides and lantibiotics.

Authors:  Michael John Dawson; Richard W Scott
Journal:  Curr Opin Pharmacol       Date:  2012-07-07       Impact factor: 5.547

2.  Heterologous production of the lantibiotic Ala(0)actagardine in Escherichia coli.

Authors:  Yanxiang Shi; Alejandro Bueno; Wilfred A van der Donk
Journal:  Chem Commun (Camb)       Date:  2012-11-18       Impact factor: 6.222

  2 in total

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