Literature DB >> 4073900

Chemical transformation of eremofortin C into PR toxin.

S Y Li, S C Chang, R D Wei.   

Abstract

The natural products of both eremofortin C (EC) and PR toxin are secondary metabolites of Penicillium roqueforti. Because the chemical structures of EC and PR toxin are closely related to each other and differ only by a hydroxyl functional group in EC and an aldehyde functional group in PR toxin at the C-12 position, the chemical transformation of EC into PR toxin was investigated. Oxidation with a chromic anhydride-pyridine complex was found to be the most satisfactory method.

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Year:  1985        PMID： 4073900      PMCID： PMC238703          DOI： 10.1128/aem.50.3.729-731.1985

Source DB:  PubMed          Journal:  Appl Environ Microbiol        ISSN： 0099-2240            Impact factor:   4.792


  9 in total

1.  Genetic effects of PR toxin in eukaryotic microorganisms.

Authors:  R Wei; T Ong; W Whong; D Frezza; G Bronzetti; E Zeiger
Journal:  Environ Mutagen       Date:  1979

2.  Production of Eremofortins A, B, and C Relative to Formation of PR Toxin by Penicillium roqueforti.

Authors:  S Moreau; A Lablache-Combier; J Biguet
Journal:  Appl Environ Microbiol       Date:  1980-04       Impact factor: 4.792

3.  In vitro metabolism of penicillium roqueforti toxin (PRT) and a structurally related compound, eremofortin A, by rat liver.

Authors:  M Cacan; S Moreau; R Tailliez
Journal:  Toxicology       Date:  1977-10       Impact factor: 4.221

4.  PR toxin production in different Penicillium roqueforti strains.

Authors:  R D Wei; G X Liu
Journal:  Appl Environ Microbiol       Date:  1978-04       Impact factor: 4.792

5.  Eremofortin C.A new metabolite obtained from penicillium roqueforti cultures and from biotransformation of PR toxin.

Authors:  S Moreau; M Cacan
Journal:  J Org Chem       Date:  1977-07-22       Impact factor: 4.354

6.  Relationships between the chemical structure and the biological properties of some eremophilane compounds related to PR toxin.

Authors:  Y Moulé; S Moreau; J F Bousquet
Journal:  Chem Biol Interact       Date:  1977-05       Impact factor: 5.192

7.  Resolution of Penicillium roqueforti toxin and eremofortins A, B, and C by high-performance liquid chromatography.

Authors:  S Moreau; A Masset; J Biguet
Journal:  Appl Environ Microbiol       Date:  1979-06       Impact factor: 4.792

8.  Isolation and partial characterization of a mycotoxin from Penicillium roqueforti.

Authors:  R D Wei; P E Still; E B Smalley; H K Schnoes; F M Strong
Journal:  Appl Microbiol       Date:  1973-01

9.  Acute toxicity of PR toxin, a mycotoxin from Penicillium roqueforti.

Authors:  F C Chen; C F Chen; R D Wei
Journal:  Toxicon       Date:  1982       Impact factor: 3.033
  9 in total

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