Biologic evaluation of filling materials. A comparison of results using cell culture techniques, implantation tests and pulp studies.

The paper presents a comparison of results from cell culture studies, implantation tests and pulp studies using silicate cement, composite material and zinc oxide/eugenol cement. The three techniques allow differentiation between reactions produced by the materials, but a poor correlation exists between the results from the different techniques. This information is considered important for a selection of techniques for biologic testing of dental materials.