Literature DB >> 4069972

Studies on tableting properties of lactose. Part 2. Consolidation and compaction of different types of crystalline lactose.

H Vromans, A H De Boer, G K Bolhuis, C F Lerk, K D Kussendrager, H Bosch.   

Abstract

Lactose is available in several crystalline forms, which differ in binding properties. A new method of estimating the fragmentation propensity was applied to investigate the consolidation and compaction behaviour of this excipient for direct compression. Mercury porosimetry was used to demonstrate that crystalline lactose fragments during compaction. Tablet strength was found to be dependent on the degree of fragmentation only. This finding indicates that the nature of the actual binding must be the same for the different types of crystalline lactose.

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Year:  1985        PMID： 4069972     DOI： 10.1007/BF02307575

Source DB:  PubMed          Journal:  Pharm Weekbl Sci        ISSN： 0167-6555


  15 in total

1.  Changes in the particle size distribution during tableting of sulphathiazole powder.

Authors:  J R Carless; A Sheak
Journal:  J Pharm Pharmacol       Date:  1976-01       Impact factor: 3.765

2.  Relations between compaction data for some crystalline pharmaceutical materials.

Authors:  E T Cole; J E Rees; J A Hersey
Journal:  Pharm Acta Helv       Date:  1975

3.  Limitations of the Heckel relation for predicting powder compaction mechanisms.

Authors:  P J Rue; J E Rees
Journal:  J Pharm Pharmacol       Date:  1978-10       Impact factor: 3.765

4.  The compaction of magnesium carbonate.

Authors:  N A Armstrong; R F Haines-Nutt
Journal:  J Pharm Pharmacol       Date:  1970-12       Impact factor: 3.765

5.  Density changes in lactose tablets.

Authors:  J A Hersey; J E Rees; E T Cole
Journal:  J Pharm Sci       Date:  1973-12       Impact factor: 3.534

6.  Effect of particle size and speed of compaction on density changes in tablets of crystalline and spray-dried lactose.

Authors:  J T Fell; J M Newton
Journal:  J Pharm Sci       Date:  1971-12       Impact factor: 3.534

7.  Surface area measurements in compressed powder systems.

Authors:  N A Armstrong; R V Griffiths
Journal:  Pharm Acta Helv       Date:  1970-09

8.  Effect on particle size on the compaction mechanism and tensile strength of tablets.

Authors:  A McKenna; D F McCafferty
Journal:  J Pharm Pharmacol       Date:  1982-06       Impact factor: 3.765

9.  Physicochemical properties of crystalline lactose. II. Effect of crystallinity on mechanical and structural properties.

Authors:  M Morita; Y Nakai; E Fukuoka; S Nakajima
Journal:  Chem Pharm Bull (Tokyo)       Date:  1984-10       Impact factor: 1.645

10.  Studies on tabletting properties of lactose, Part I. The effect of initial particle size on binding properties and dehydration characteristics of lactose.

Authors:  H Vromans; A H de Boer; G K Bolhuis; C F Lerk; K D Kussendrager
Journal:  Acta Pharm Suec       Date:  1985
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  10 in total

1.  Assessing tablet bond types from structural features that affect tablet tensile strength.

Authors:  H Olsson; C Nyström
Journal:  Pharm Res       Date:  2001-02       Impact factor: 4.200

2.  Location-dependent analysis of porosity and pore direction in tablets.

Authors:  Yu San Wu; Henderik W Frijlink; Lucas J van Vliet; Ietse Stokroos; Kees van der Voort Maarschalk
Journal:  Pharm Res       Date:  2005-08-03       Impact factor: 4.200

3.  Predicting the tensile strength of compacted multi-component mixtures of pharmaceutical powders.

Authors:  Chuan-Yu Wu; Serena M Best; A Craig Bentham; Bruno C Hancock; William Bonfield
Journal:  Pharm Res       Date:  2006-08       Impact factor: 4.200

4.  Percolation theory and compactibility of binary powder systems.

Authors:  D Blattner; M Kolb; H Leuenberger
Journal:  Pharm Res       Date:  1990-02       Impact factor: 4.200

5.  Use of first derivative of displacement vs. force profiles to determine deformation behavior of compressed powders.

Authors:  Shadi F Gharaibeh; Aktham Aburub
Journal:  AAPS PharmSciTech       Date:  2013-01-24       Impact factor: 3.246

6.  Studies on tableting properties of lactose. Part III. The consolidation behaviour of sieve fractions of crystalline alpha-lactose monohydrate.

Authors:  A H De Boer; H Vromans; C F Lerk; G K Bolhuis; K D Kussendrager; H Bosch
Journal:  Pharm Weekbl Sci       Date:  1986-04-25

7.  The effect of particle fragmentation and deformation on the interparticulate bond formation process during powder compaction.

Authors:  M Eriksson; G Alderborn
Journal:  Pharm Res       Date:  1995-07       Impact factor: 4.200

8.  Thermal Stability and Kinetic Study of Fluvoxamine Stability in Binary Samples with Lactose.

Authors:  Faranak Ghaderi; Mahboob Nemati; Mohammad Reza Siahi-Shadbad; Hadi Valizadeh; Farnaz Monajjemzadeh
Journal:  Adv Pharm Bull       Date:  2017-04-13

9.  The Novel Use of PVP K30 as Templating Agent in Production of Porous Lactose.

Authors:  Wei-Feng Zhu; Lin Zhu; Zhe Li; Wen-Ting Wu; Yong-Mei Guan; Li-Hua Chen; Zhi-Xuan Mao; Liang-Shan Ming
Journal:  Pharmaceutics       Date:  2021-05-30       Impact factor: 6.321

10.  Formulation and Characterization of an Effervescent Hydrogen-Generating Tablet.

Authors:  Moritz Rosch; Kurt Lucas; Jozef Al-Gousous; Ulrich Pöschl; Peter Langguth
Journal:  Pharmaceuticals (Basel)       Date:  2021-12-18
  10 in total

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