Literature DB >> 4069226

[Vitamin D-binding protein in human plasma. Analysis of genetic variation].

H Cleve.   

Abstract

The vitamin-D-binding protein (DBP) also known as group-specific component (GC) is described. This transport protein for vitamin D and its metabolic derivatives has genetic variants which are disclosed by electrophoretic procedures or by isoelectric focusing. Three common and one hundred rare alleles are known. The biochemical, molecular and population genetics are briefly outlined as an example of inherited variability in man.

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Year:  1985        PMID： 4069226     DOI： 10.1007/BF00367597

Source DB:  PubMed          Journal:  Naturwissenschaften        ISSN： 0028-1042


  41 in total

1.  Gc subtypes demonstrated by isoelectric focusing: further data and description of new variants among an African sample (Fula) from Senegal.

Authors:  J Constans; M Viau; G Pison; A Langaney
Journal:  Jinrui Idengaku Zasshi       Date:  1978-06

2.  The polymorphism of the vitamin D-binding protein (Gc); isoelectric focusing in 3 M urea as additional method for identification of genetic variants.

Authors:  J Constans; H Cleve; D Dykes; M Fischer; R L Kirk; S S Papiha; W Scheffran; R Scherz; M Thymann; W Weber
Journal:  Hum Genet       Date:  1983       Impact factor: 4.132

3.  A new single band variant of the Gc subtypes determined by isoelectric focusing.

Authors:  I Nakasono; M Iwasaki; M Ogata; C Yoshida; T Yoshitake; K Narita; H Suyama; Y Tomohiro
Journal:  Hum Genet       Date:  1983       Impact factor: 4.132

4.  Induction of monocytic differentiation and bone resorption by 1,25-dihydroxyvitamin D3.

Authors:  Z Bar-Shavit; S L Teitelbaum; P Reitsma; A Hall; L E Pegg; J Trial; A J Kahn
Journal:  Proc Natl Acad Sci U S A       Date:  1983-10       Impact factor: 11.205

5.  Studies of antiricketic activity in sera from patients with disorders of calcium metabolism and preliminary observations on the mode of transport of vitamin D in human serum.

Authors:  W C THOMAS; H G MORGAN; T B CONNOR; L HADDOCK; C E BILLS; J E HOWARD
Journal:  J Clin Invest       Date:  1959-07       Impact factor: 14.808

6.  Neuraminidase treatment reveals sialic acid differences in certain genetic variants of the Gc system (vitamin-D-binding protein).

Authors:  H Cleve; W Patutschnick
Journal:  Hum Genet       Date:  1979-03-12       Impact factor: 4.132

7.  Group-specific component (Gc) and transferrin (Tf) subtypes ascertained by isoelectric focusing. A simple nonimmunological staining procedure for Gc.

Authors:  B Hoste
Journal:  Hum Genet       Date:  1979       Impact factor: 4.132

8.  The vitamin D binding of the common and rare variants of the group-specific component (Gc). An autoradiographic study.

Authors:  H Cleve; W Patutschnick
Journal:  Hum Genet       Date:  1977-10-14       Impact factor: 4.132

9.  Possible localization of Gc-System on chromosome 4. Loss of long arm 4 material associated with father-child incompatibility within the Gc-System.

Authors:  M Mikkelsen; P Jacobsen; K Henningsen
Journal:  Hum Hered       Date:  1977       Impact factor: 0.444

10.  Gc subtypes determined by agarose isoelectrofocusing: distribution in Denmark and application to paternity cases.

Authors:  M Thymann
Journal:  Hum Hered       Date:  1981       Impact factor: 0.444
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  2 in total

1.  AIDS: no association with the genetic systems GC (D-binding protein), ORM (orosomucoid = alpha-1-acid glycoprotein), and A2HS (alpha-2-HS-glycoprotein).

Authors:  H Cleve; S Weidinger; L G Gürtler; F Deinhardt
Journal:  Infection       Date:  1988       Impact factor: 3.553

2.  High PD-L1 expression is associated with therapeutic response to pembrolizumab in patients with advanced biliary tract cancer.

Authors:  Soomin Ahn; Jong-Chan Lee; Dong Woo Shin; Jaihwan Kim; Jin-Hyeok Hwang
Journal:  Sci Rep       Date:  2020-07-23       Impact factor: 4.379
  2 in total

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