Literature DB >> 3162895

AIDS: no association with the genetic systems GC (D-binding protein), ORM (orosomucoid = alpha-1-acid glycoprotein), and A2HS (alpha-2-HS-glycoprotein).

H Cleve1, S Weidinger, L G Gürtler, F Deinhardt.   

Abstract

In a sample of 97 HIV-1 seropositive persons which comprised 34 patients with AIDS, 30 patients with persistent generalized lymphadenopathy or with AIDS related complex and 33 persons who were without symptoms and called "healthy", three genetic marker systems were examined: 1) GC, the group-specific component of serum which is identical with the vitamin D binding protein (DBP) of serum, 2) ORM, the acute phase protein orosomucoid = alpha-1-acid glycoprotein of serum, and 3) A2HS, the alpha-2-AS glycoprotein of serum. The distribution of the genotypes and of the alleles in the sample of AIDS patients and of HIV-1/positive persons was not different from the distribution in control groups. An association between susceptibility and/or resistance for AIDS and these genetic marker systems was not observed.

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Year:  1988        PMID: 3162895     DOI: 10.1007/bf01646929

Source DB:  PubMed          Journal:  Infection        ISSN: 0300-8126            Impact factor:   3.553


  20 in total

1.  THE DYNAMICS OF THE GC POLYMORPHISM IN A BRAZILIAN POPULATION.

Authors:  F M SALZANO; H HIRSCHFELD
Journal:  Acta Genet Stat Med       Date:  1965

2.  Genetic studies on the Gc subtypes.

Authors:  H Cleve; W Patutschnick; S Nevo; G G Wendt
Journal:  Hum Genet       Date:  1978-10-31       Impact factor: 4.132

3.  Hp, Gc, Cp, Tf, Bg and Pi phenotypes in leprosy patients and healthy controls from West Bengal (India).

Authors:  H Walter; G Kellermann; M Bajatzadeh; J Krüger; M R Chakravartti
Journal:  Humangenetik       Date:  1972

4.  Genetic studies in relation to kuru. 3. Distribution of the inherited serum group-specific protein (Ge) phenotypes in New Guineans: an association of kuru and the Gc Ab phenotype.

Authors:  F D Kitchin; A G Bearn; M Alpers; D C Gajdusek
Journal:  Am J Hum Genet       Date:  1972-11       Impact factor: 11.025

5.  Association between response to typhoid vaccination and known genetic markers.

Authors:  S S Nevo; H E Sutton
Journal:  Am J Hum Genet       Date:  1968-09       Impact factor: 11.025

6.  AIDS and the Gc protein.

Authors: 
Journal:  Lancet       Date:  1987-06-13       Impact factor: 79.321

7.  A new single band variant of the Gc subtypes determined by isoelectric focusing.

Authors:  I Nakasono; M Iwasaki; M Ogata; C Yoshida; T Yoshitake; K Narita; H Suyama; Y Tomohiro
Journal:  Hum Genet       Date:  1983       Impact factor: 4.132

8.  Group-specific component: evidence for two subtypes of the Gc1 gene.

Authors:  J Constans; M Viau
Journal:  Science       Date:  1977-12-09       Impact factor: 47.728

9.  Three new orosomucoid (ORM) variants revealed by isoelectric focusing and print immunofixation.

Authors:  S Weidinger; T Müller; F Schwarzfischer; H Cleve
Journal:  Hum Genet       Date:  1987-11       Impact factor: 4.132

10.  Neuraminidase treatment reveals sialic acid differences in certain genetic variants of the Gc system (vitamin-D-binding protein).

Authors:  H Cleve; W Patutschnick
Journal:  Hum Genet       Date:  1979-03-12       Impact factor: 4.132

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  3 in total

1.  Changes in the levels of some acute-phase proteins in human immunodeficiency virus-1 infected patients, following interleukin-2 treatment.

Authors:  V H Barbai; E Ujhelyi; J Szlávik; I Vietorisz; L Varga; E Fey; G Füst; D Bánhegyi
Journal:  Clin Exp Immunol       Date:  2010-04-09       Impact factor: 4.330

2.  DBP rs16846876 and rs12512631 polymorphisms are associated with progression to AIDS naïve HIV-infected patients: a retrospective study.

Authors:  María Ángeles Jiménez-Sousa; José Luis Jiménez; Amanda Fernández-Rodríguez; José María Bellón; Carmen Rodríguez; Melchor Riera; Joaquín Portilla; Ángeles Castro; María Ángeles Muñoz-Fernández; Salvador Resino
Journal:  J Biomed Sci       Date:  2019-10-23       Impact factor: 8.410

Review 3.  Common variants of the vitamin D binding protein gene and adverse health outcomes.

Authors:  Suneil Malik; Lei Fu; David James Juras; Mohamed Karmali; Betty Y L Wong; Agnes Gozdzik; David E C Cole
Journal:  Crit Rev Clin Lab Sci       Date:  2013-02-22       Impact factor: 6.250

  3 in total

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