Literature DB >> 406894

Purine nucleoside phosphorylase polymorphism in sheep erythrocytes.

P G Board, J E Smith.   

Abstract

A polymorphism of purine nucleoside phosphorylase is described in sheep erythrocytes. Two isozymes were distinguished electrophoretically, one with high activity (NP-1) and one with low activity (NP-2). Breeding data suggest that the two isozymes are the product of two codominant alleles, NP1 and NP2. The Km's for inosine did not differ between NP-1 and NP-2; however, NP-2 had a lower pH optimum and was relatively unstable when incubated at 48 C.

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Year:  1977        PMID： 406894     DOI： 10.1007/bf00520189

Source DB:  PubMed          Journal:  Biochem Genet        ISSN： 0006-2928            Impact factor:   1.890


  4 in total

1.  Note on a third allele in the erythrocytic NP system of cattle.

Authors:  M Ansay
Journal:  Anim Blood Groups Biochem Genet       Date:  1975

2.  Differential spectrophotometry of purine compounds by means of specific enzymes; studies of the enzymes of purine metabolism.

Authors:  H M KALCKAR
Journal:  J Biol Chem       Date:  1947-02       Impact factor: 5.157

3.  Biochemical variants of glucose-6-phosphate dehydrogenase giving rise to congenital nonspherocytic hemolytic disease.

Authors:  E Beutler; C K Mathai; J E Smith
Journal:  Blood       Date:  1968-02       Impact factor: 22.113

4.  Inherited variants of human nucleoside phosphorylase.

Authors:  Y H Edwards; D A Hopkinson; H Harris
Journal:  Ann Hum Genet       Date:  1971-05       Impact factor: 1.670
  4 in total
  2 in total

1.  Purine nucleoside phosphorylase variation in the brook lamprey, Lampetra planeri (Bloch) (Petromyzone, Agnatha): evidence for a trimeric enzyme structure.

Authors:  R D Ward; B J McAndrew; G P Wallis
Journal:  Biochem Genet       Date:  1979-04       Impact factor: 1.890

2.  Genetic variability of purine nucleoside phosphorylase activity in the mouse: relationship to Np-1 and Np-2.

Authors:  F F Snyder; F G Biddle; T Lukey; M J Sparling
Journal:  Biochem Genet       Date:  1983-04       Impact factor: 1.890
  2 in total

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