Literature DB >> 6407470

Genetic variability of purine nucleoside phosphorylase activity in the mouse: relationship to Np-1 and Np-2.

F F Snyder, F G Biddle, T Lukey, M J Sparling.   

Abstract

A survey of 37 inbred strains for erythrocyte purine nucleoside phosphorylase activity showed a greater than threefold range. Six of these strains had significantly greater activity than the others, and all of the high-activity strains had the Np-2 electrophoretic band. The high-purine nucleoside phosphorylase activity trait corresponding to Np-2 was inherited in an autosomal codominant manner and minor differences were apparent in thermal and kinetic properties between low- and high-activity strains. This work provides further support for there being either two structural loci for purine nucleoside phosphorylase, Np-1 and Np-2, or a regulatory-modifier locus.

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Year:  1983        PMID： 6407470     DOI： 10.1007/BF00499142

Source DB:  PubMed          Journal:  Biochem Genet        ISSN： 0006-2928            Impact factor:   1.890


  12 in total

1.  Myoglobin: in herited structural variation in man.

Authors:  S H BOYER; D C FAINER; M A NAUGHTON
Journal:  Science       Date:  1963-06-14       Impact factor: 47.728

2.  Comparison of normal blood picture of young adults from 18 inbred strains of mice.

Authors:  E S RUSSELL; E F NEUFELD; C T HIGGINS
Journal:  Proc Soc Exp Biol Med       Date:  1951-12

3.  Assignment of the gene for adenosine kinase to chromosome 14 in Mus musculus by somatic cell hybridization.

Authors:  L Leinwand; R E Fournier; E A Nichols; F H Ruddle
Journal:  Cytogenet Cell Genet       Date:  1978

4.  Effects of 2'-deoxycoformycin infusion on mouse adenosine deaminase.

Authors:  A Tedde; M E Balis; R Schonberg; P P Trotta
Journal:  Cancer Res       Date:  1979-08       Impact factor: 12.701

5.  Nucleoside phosphorylase 2 (Np-2) of mice.

Authors:  T A Bremner; E Premkumar-Reddy; K Nayar; R E Kouri
Journal:  Biochem Genet       Date:  1978-12       Impact factor: 1.890

6.  Adenosine metabolism in phytohemagglutinin-stimulated human lymphocytes.

Authors:  F F Snyder; J Mendelsohn; J E Seegmiller
Journal:  J Clin Invest       Date:  1976-09       Impact factor: 14.808

7.  Purine ribonucleoside and deoxyribonucleoside kinase activities in thymocytes. Specificity and optimal assay conditions for phosphorylation.

Authors:  T Lukey; F F Snyder
Journal:  Can J Biochem       Date:  1980-09

8.  Mapping of nucleoside phosphorylase (Np-1) and esterase 10 (Es-10) on mouse chromosome 14.

Authors:  J E Womack; M T Davisson; E M Eicher; D A Kendall
Journal:  Biochem Genet       Date:  1977-04       Impact factor: 1.890

9.  Nucleoside-phosphorylase deficiency in a child with severely defective T-cell immunity and normal B-cell immunity.

Authors:  E R Giblett; A J Ammann; D W Wara; R Sandman; L K Diamond
Journal:  Lancet       Date:  1975-05-03       Impact factor: 79.321

10.  Elucidation of aberrant purine metabolism: application to hypoxanthine-guanine phosphoribosylstransferase- and adenosine kinase-deficient mutants, and IMP dehydrogenase- and adenosine deaminase-inhibited human lymphoblasts.

Authors:  F F Snyder; R J Trafzer; M S Hershfield; J E Seegmiller
Journal:  Biochim Biophys Acta       Date:  1980-10-17
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  4 in total

Review 1.  Mouse chromosome 14.

Authors:  J H Nadeau; R Cox
Journal:  Mamm Genome       Date:  1992       Impact factor: 2.957

Review 2.  Mouse chromosome 14.

Authors:  J H Nadeau; J D Ceci; R Cox
Journal:  Mamm Genome       Date:  1991       Impact factor: 2.957

3.  cDNA sequence of four purine nucleoside phosphorylase (Np) alleles in the mouse.

Authors:  J P Jenuth; R K Mangat; F F Snyder
Journal:  Mamm Genome       Date:  1993       Impact factor: 2.957

4.  Purine nucleoside phosphorylase (Np) in the mouse: linkage relationship of Np-2 to esterase-10 (Es-10) and Np-1 on chromosome 14.

Authors:  T Lukey; K Neote; J F Loman; A E Unger; F G Biddle; F F Snyder
Journal:  Biochem Genet       Date:  1985-04       Impact factor: 1.890
  4 in total

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