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Literature DB >> 406862

Inhibition by gold of human lymphocyte stimulation. An in vitro study.

Abstract

Transformation of lymphocytes stimulated by mitogen, purified protein derivative, and in the mixed lymphocyte culture was significantly inhibited by gold sodium thiomate and gold sodium thiosulphate at concentrations of 5 X 10(-4) to 5 X 10(-5) mol/1.

Entities: Chemical Species

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Year: 1977 PMID： 406862 PMCID： PMC1006668 DOI： 10.1136/ard.36.3.216

Source DB: PubMed Journal: Ann Rheum Dis ISSN： 0003-4967 Impact factor: 19.103

5 in total

1. The role of the lymphocyte and its products in the propagation of joint disease.

Authors: C M Pearson; H E Paulus; H I Machleder
Journal: Ann N Y Acad Sci Date: 1975-06-13 Impact factor: 5.691

Review 2. Cellular immunological aspects of rheumatoid arthritis.

Authors: D T Yu; J B Peter
Journal: Semin Arthritis Rheum Date: 1974 Impact factor: 5.532

3. Efficacy of immunosuppressive drugs in rheumatic diseases.

Authors: A D Steinberg
Journal: Arthritis Rheum Date: 1973 Jan-Feb

4. Effects of azathioprine therapy on bone marrow-dependent and thymus-dependent cells in man.

Authors: N I Abdou; B Zweiman; S R Casella
Journal: Clin Exp Immunol Date: 1973-01 Impact factor: 4.330

5. Tissue gold concentration in a rheumatoid arthritic receiving chrysotherapy.

Authors: N L Gottlieb; P M Smith; E M Smith
Journal: Arthritis Rheum Date: 1972 Jan-Feb

5 in total

11 in total

1. A survey of the effect of metals on the immune response.

Authors: L Treagan
Journal: Biol Trace Elem Res Date: 1979-06 Impact factor: 3.738

2. The immunological consequences of gold therapy: a prospective study in patients with rheumatoid arthritis.

Authors: J Hassan; J Hanly; B Bresnihan; C Feighery; C A Whelan
Journal: Clin Exp Immunol Date: 1986-03 Impact factor: 4.330

3. Metabolism of intracellular zinc and copper following single and repeated injections of gold sodium thiomalate.

Authors: R P Sharma
Journal: Agents Actions Date: 1983-06

4. Inhibition of lymphocyte activation by gold sodium thiomalate.

Authors: S J Hopkins; M I Jayson; P Van der Zeil
Journal: Br J Pharmacol Date: 1983-06 Impact factor: 8.739

5. In vitro effects of gold sodium thiomalate on IL-1, IL-2 production, IL-2 receptor expression and IL-2 responsiveness in thymocytes and peripheral blood mononuclear cells.

Authors: E Blitstein-Willinger; A Streller
Journal: Clin Exp Immunol Date: 1987-05 Impact factor: 4.330

Inhibition by gold of human lymphocyte stimulation. An in vitro study.

1. The role of the lymphocyte and its products in the propagation of joint disease.

Review 2. Cellular immunological aspects of rheumatoid arthritis.

3. Efficacy of immunosuppressive drugs in rheumatic diseases.

4. Effects of azathioprine therapy on bone marrow-dependent and thymus-dependent cells in man.

5. Tissue gold concentration in a rheumatoid arthritic receiving chrysotherapy.

1. A survey of the effect of metals on the immune response.

2. The immunological consequences of gold therapy: a prospective study in patients with rheumatoid arthritis.

3. Metabolism of intracellular zinc and copper following single and repeated injections of gold sodium thiomalate.

4. Inhibition of lymphocyte activation by gold sodium thiomalate.

5. In vitro effects of gold sodium thiomalate on IL-1, IL-2 production, IL-2 receptor expression and IL-2 responsiveness in thymocytes and peripheral blood mononuclear cells.

6. Inhibition of mycoplasma-induced lymphocyte activation by sodium aurothiomalate.

7. Effect of gold sodium thiomalate on murine lymphocyte functions.

8. The effect of clotrimazole on human lymphocyte responsiveness to plant mitogens.

9. Inhibition of reticuloendothelial function by gold and its relation to postinjection reactions.

10. Reduction of peripheral blood lymphocytes in patients receiving gold therapy for rheumatoid arthritis.