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Literature DB >> 4062880

Masticatory lubrication. The role of carbohydrate in the lubricating property of a salivary glycoprotein-albumin complex.

M N Hatton, R E Loomis, M J Levine, L A Tabak.

Abstract

We report for the first time a masticatory-lubrication assay system to assess the lubricating properties of salivary constituents. The lubricating ability of the proline-rich glycoprotein (PRG) of parotid saliva was enhanced by human serum albumin. The interactive effect of albumin was abolished by chemically deglycosylating the glycoprotein. Fluorescence spectroscopy with a hydrophobic probe verified the existence of a PRG-albumin complex and demonstrated that deglycosylation of the PRG altered the nature of its interaction with albumin.

Entities: Chemical Disease Gene Species

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Year: 1985 PMID： 4062880 PMCID： PMC1152688 DOI： 10.1042/bj2300817

Source DB: PubMed Journal: Biochem J ISSN： 0264-6021 Impact factor: 3.857

12 in total

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15 in total

1. Comparison of N-linked Glycoproteins in Human Whole Saliva, Parotid, Submandibular, and Sublingual Glandular Secretions Identified using Hydrazide Chemistry and Mass Spectrometry.

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Journal: Clin Proteomics Date: 2008-12 Impact factor: 3.988

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Journal: Biophys J Date: 2010-07-21 Impact factor: 4.033

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