Literature DB >> 4058751

Dexamethasone treatment of brain tumor patients: effects on regional cerebral blood flow, blood volume, and oxygen utilization.

K L Leenders, R P Beaney, D J Brooks, A A Lammertsma, J D Heather, C G McKenzie.   

Abstract

Regional values for cerebral blood flow, blood volume, oxygen extraction fraction, and oxygen utilization were measured, using PET, in 10 brain tumor patients before and after treatment with dexamethasone. Dexamethasone treatment decreased cerebral blood flow and blood volume and increased the fractional extraction of oxygen throughout the brain without affecting oxygen utilization. Dexamethasone probably causes direct vasoconstriction of cerebral blood vessels.

Entities:  

Mesh：

Substances：

Year:  1985        PMID： 4058751     DOI： 10.1212/wnl.35.11.1610

Source DB:  PubMed          Journal:  Neurology        ISSN： 0028-3878            Impact factor:   9.910


  30 in total

1.  Changes in glucose uptake by malignant gliomas: preliminary study of prognostic significance.

Authors:  J M Rozental; R L Levine; R J Nickles
Journal:  J Neurooncol       Date:  1991-02       Impact factor: 4.130

2.  Quantitative oxygenation venography from MRI phase.

Authors:  Audrey P Fan; Berkin Bilgic; Louis Gagnon; Thomas Witzel; Himanshu Bhat; Bruce R Rosen; Elfar Adalsteinsson
Journal:  Magn Reson Med       Date:  2013-09-04       Impact factor: 4.668

3.  Hyperperfusion in progressive multifocal leukoencephalopathy is associated with disease progression and absence of immune reconstitution inflammatory syndrome.

Authors:  Michael N Khoury; Sarah Gheuens; Long Ngo; Xiaoen Wang; David C Alsop; Igor J Koralnik
Journal:  Brain       Date:  2013-10-01       Impact factor: 13.501

4.  Evaluation of hyperglycaemic response to intra-operative dexamethasone administration in patients undergoing elective intracranial surgery: A randomised, prospective study.

Authors:  Rakesh Sethi; Imtiaz A Naqash; Sukhminder Jit Singh Bajwa; Vikas Dutta; Altaf Umar Ramzan; Syed Amir Zahoor
Journal:  Asian J Neurosurg       Date:  2016 Apr-Jun

5.  Cerebral diaschisis in patients with malignant glioma.

Authors:  J M Rozental; R L Levine; R J Nickles; J A Dobkin; J M Hanson
Journal:  J Neurooncol       Date:  1990-04       Impact factor: 4.130

6.  Temporal effects of dexamethasone on blood-to-brain and blood-to-tumor transport of 14C-alpha-aminoisobutyric acid in rat C6 glioma.

Authors:  W R Shapiro; E M Hiesiger; G A Cooney; G A Basler; L E Lipschutz; J B Posner
Journal:  J Neurooncol       Date:  1990-06       Impact factor: 4.130

7.  Dynamic MRI using iron oxide nanoparticles to assess early vascular effects of antiangiogenic versus corticosteroid treatment in a glioma model.

Authors:  Csanad G Varallyay; Leslie L Muldoon; Seymur Gahramanov; Yingjen J Wu; James A Goodman; Xin Li; Martin M Pike; Edward A Neuwelt
Journal:  J Cereb Blood Flow Metab       Date:  2009-01-14       Impact factor: 6.200

8.  Intravascular contrast agent T2* relaxivity in brain tissue.

Authors:  Vishal Patil; Jens H Jensen; Glyn Johnson
Journal:  NMR Biomed       Date:  2012-12-06       Impact factor: 4.044

9.  Measurement of changes in brain water in man by magnetic resonance imaging.

Authors:  B A Bell
Journal:  Ann R Coll Surg Engl       Date:  1989-11       Impact factor: 1.891

10.  Glucocorticoid treatment of brain tumor patients: changes of apparent diffusion coefficient values measured by MR diffusion imaging.

Authors:  Sosuke Minamikawa; Kinuko Kono; Keiko Nakayama; Hiroyuki Yokote; Takahiko Tashiro; Akimasa Nishio; Mitsuhiro Hara; Yuichi Inoue
Journal:  Neuroradiology       Date:  2004-10       Impact factor: 2.804
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.