Literature DB >> 4052794

Calcium influx in cultured carotid body cells is stimulated by acetylcholine and hypoxia.

F Pietruschka.   

Abstract

Calcium influx was measured in cultured carotid body and glioma cells. In carotid body cells stimulation with acetylcholine (ACh, 10(-5) mol/l) increased the calcium influx to 135% of control values after 1 min and to 163% after 30 min. With a reduction of the pO2 to nearly zero calcium influx increased to 170% of control values. In glioma cells there was only a slight or no increase. This sensitivity of carotid body cells is discussed in relation to their function in chemoreception.

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Year:  1985        PMID: 4052794     DOI: 10.1016/0006-8993(85)90901-1

Source DB:  PubMed          Journal:  Brain Res        ISSN: 0006-8993            Impact factor:   3.252


  4 in total

1.  Involvement of an NAD(P)H oxidase as a pO2 sensor protein in the rat carotid body.

Authors:  A R Cross; L Henderson; O T Jones; M A Delpiano; J Hentschel; H Acker
Journal:  Biochem J       Date:  1990-12-15       Impact factor: 3.857

Review 2.  Peripheral chemoreceptors: function and plasticity of the carotid body.

Authors:  Prem Kumar; Nanduri R Prabhakar
Journal:  Compr Physiol       Date:  2012-01       Impact factor: 9.090

Review 3.  Transduction of chemostimuli by the type I carotid body cell.

Authors:  C Peers; K J Buckler
Journal:  J Membr Biol       Date:  1995-03       Impact factor: 1.843

4.  Muscarinic and nicotinic receptors raise intracellular Ca2+ levels in rat carotid body type I cells.

Authors:  L L Dasso; K J Buckler; R D Vaughan-Jones
Journal:  J Physiol       Date:  1997-01-15       Impact factor: 5.182

  4 in total

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