Literature DB >> 4039080

Protective effect of metallothionein inducing metals on lethal toxicity of cis-diamminedichloroplatinum in mice.

A Naganuma, M Satoh, Y Koyama, N Imura.   

Abstract

A protective effect of preadministration of the metals Cu, Bi, Zn, Hg, Cd, Ni or Co, against lethal toxicity of cis-diamminedichloroplatinum (Cisplatin; CDDP) was observed in mice. However, the protective effect seems not always to correlate with metallothionein (MT) levels in the liver and kidney of mice treated with one of these metals, suggesting possible participation in this protection of mechanisms other than MT induction by the preadministered metals.

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Year:  1985        PMID： 4039080     DOI： 10.1016/0378-4274(85)90058-x

Source DB:  PubMed          Journal:  Toxicol Lett        ISSN： 0378-4274            Impact factor:   4.372


  7 in total

1.  Metallothionein-like proteins and cell resistance to cis-dichlorodiammineplatinum(II) in L1210 cells.

Authors:  P Farnworth; B Hillcoat; I Roos
Journal:  Cancer Chemother Pharmacol       Date:  1990       Impact factor: 3.333

2.  Metallothionein induction prevents toxic side effects of cisplatin and adriamycin used in combination.

Authors:  M Satoh; A Naganuma; N Imura
Journal:  Cancer Chemother Pharmacol       Date:  1988       Impact factor: 3.333

3.  Zinc acetate pretreatment ameliorates cisplatin-induced Sertoli cell dysfunction in Sprague-Dawley rats.

Authors:  L M Pogach; Y Lee; W Giglio; M Naumoff; H F Huang
Journal:  Cancer Chemother Pharmacol       Date:  1989       Impact factor: 3.333

4.  Experimental basis for increasing the therapeutic index of cis-diamminedicarboxylatocyclobutaneplatinum(II) in brain tumor therapy by a high-zinc diet.

Authors:  F Doz; M E Berens; C F Deschepper; D V Dougherty; V Bigornia; M Barker; M L Rosenblum
Journal:  Cancer Chemother Pharmacol       Date:  1992       Impact factor: 3.333

Review 5.  WR2721 as a modulator of cisplatin- and carboplatin-induced side effects in comparison with other chemoprotective agents: a molecular approach.

Authors:  M Treskes; W J van der Vijgh
Journal:  Cancer Chemother Pharmacol       Date:  1993       Impact factor: 3.333

Review 6.  Metallothionein and anticancer agents: the role of metallothionein in cancer chemotherapy.

Authors:  F Doz; N Roosen; M L Rosenblum
Journal:  J Neurooncol       Date:  1993-08       Impact factor: 4.130

7.  Specific reduction of toxic side effects of adriamycin by induction of metallothionein in mice.

Authors:  A Naganuma; M Satoh; N Imura
Journal:  Jpn J Cancer Res       Date:  1988-03
  7 in total

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