Literature DB >> 4037011

Management of stage IA carcinoma of the cervix.

W T Creasman, B F Fetter, D L Clarke-Pearson, L Kaufmann, R T Parker.   

Abstract

One hundred fourteen patients with Stage IA carcinoma of the cervix were retrospectively reviewed in regard to depth of invasion, capillary-like space involvement, stromal reaction, status of conization margins, and the incidence of lymph node metastasis. Type of treatment, recurrences, and deaths were also evaluated. Patients with less than 3 mm invasion can be treated conservatively, including conization, if fertility is desired. No lymph node metastasis or recurrence appeared in this group of patients irrespective of type of treatment. Patients with 3 to 5 mm invasion do appear to be at higher risk for recurrence, but conservative therapy may be used in individualized situations. Size of conization and status of surgical margins appear to be important determining factors in regard to conservative therapy. Data in the literature, as well as our experience, although limited, suggest that the status of capillary-like space involvement does not influence lymph node metastasis or recurrence. Invasion of 5 mm or more in depth should be treated as a Stage IB occult lesion.

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Mesh:

Year:  1985        PMID: 4037011     DOI: 10.1016/0002-9378(85)90105-x

Source DB:  PubMed          Journal:  Am J Obstet Gynecol        ISSN: 0002-9378            Impact factor:   8.661


  6 in total

Review 1.  The pattern is the issue: recent advances in adenocarcinoma of the uterine cervix.

Authors:  Andres A Roma; Oluwole Fadare
Journal:  Virchows Arch       Date:  2018-02-05       Impact factor: 4.064

2.  New pattern-based personalized risk stratification system for endocervical adenocarcinoma with important clinical implications and surgical outcome.

Authors:  Andres A Roma; Toni-Ann Mistretta; Andrea Diaz De Vivar; Kay J Park; Isabel Alvarado-Cabrero; Golnar Rasty; Jose G Chanona-Vilchis; Yoshiki Mikami; Sung R Hong; Norihiro Teramoto; Rouba Ali-Fehmi; Denise Barbuto; Joanne K L Rutgers; Elvio G Silva
Journal:  Gynecol Oncol       Date:  2016-04       Impact factor: 5.482

3.  Psychosexual implications of gynaecological cancer.

Authors:  M E Crowther; R H Corney; J H Shepherd
Journal:  BMJ       Date:  1994-04-02

4.  Preoperative pathologic findings associated with residual disease at radical hysterectomy in women with stage IA2 cervical cancer.

Authors:  Anuj Suri; Michael Frumovitz; Michael R Milam; Ricardo dos Reis; Pedro T Ramirez
Journal:  Gynecol Oncol       Date:  2008-10-25       Impact factor: 5.482

Review 5.  Early cervical cancer.

Authors:  K H Lu; T W Burke
Journal:  Curr Treat Options Oncol       Date:  2000-06

6.  Using decision analysis to calculate the optimum treatment for microinvasive cervical cancer.

Authors:  N Johnson; R J Lilford; S E Jones; L McKenzie; P Billingsley; F F Songane
Journal:  Br J Cancer       Date:  1992-05       Impact factor: 7.640

  6 in total

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