Literature DB >> 403608

Antileukemia activity in the Osillatoriaceae: isolation of Debromoaplysiatoxin from Lyngbya.

J S Mynderse, R E Moore, M Kashiwagi, T R Norton.   

Abstract

Chloroform extracts of several seaweeds, of the family Oscillatoriaceae, from Enewetak Atoll, Marshall Islands, display activity against P-388 lymphocytic mouse leukemia. A P-388 active compound, debromoaplysiatoxin, has been isolated from Lyngbya gracilis and characterized. This compound also has dermonecrotic activity and may be the dermatitis-producing substance in L. majuscula, the causative agent of "swimmers' itch" outbreaks in Hawaiian waters.

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Year:  1977        PMID： 403608     DOI： 10.1126/science.403608

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  25 in total

Review 1.  Algal biotechnology.

Authors:  R J Cannell
Journal:  Appl Biochem Biotechnol       Date:  1990-10       Impact factor: 2.926

Review 2.  Biologically active secondary metabolites from marine cyanobacteria.

Authors:  Joshawna K Nunnery; Emily Mevers; William H Gerwick
Journal:  Curr Opin Biotechnol       Date:  2010-10-26       Impact factor: 9.740

3.  Algal toxins.

Authors:  M Collins
Journal:  Microbiol Rev       Date:  1978-12

4.  Chemical ecology of marine organisms: An overview.

Authors:  G J Bakus; N M Targett; B Schulte
Journal:  J Chem Ecol       Date:  1986-05       Impact factor: 2.626

5.  Nhatrangins A and B, aplysiatoxin-related metabolites from the marine cyanobacterium Lyngbya majuscula from Vietnam.

Authors:  George E Chlipala; Huu Tri Pham; Van Hung Nguyen; Aleksej Krunic; Sang Hee Shim; D Doel Soejarto; Jimmy Orjala
Journal:  J Nat Prod       Date:  2010-04-23       Impact factor: 4.050

6.  Indole alkaloids: dihydroteleocidin B, teleocidin, and lyngbyatoxin A as members of a new class of tumor promoters.

Authors:  H Fujiki; M Mori; M Nakayasu; M Terada; T Sugimura; R E Moore
Journal:  Proc Natl Acad Sci U S A       Date:  1981-06       Impact factor: 11.205

7.  Effect of biological toxins on gap-junctional intercellular communication in Chinese hamster V79 cells.

Authors:  C Jone; L Erickson; J E Trosko; C C Chang
Journal:  Cell Biol Toxicol       Date:  1987-03       Impact factor: 6.691

8.  Viridamides A and B, lipodepsipeptides with antiprotozoal activity from the marine cyanobacterium Oscillatoria nigro-viridis.

Authors:  T Luke Simmons; Niclas Engene; Luis David Ureña; Luz I Romero; Eduardo Ortega-Barría; Lena Gerwick; William H Gerwick
Journal:  J Nat Prod       Date:  2008-08-21       Impact factor: 4.050

9.  Assessing pressurized liquid extraction for the high-throughput extraction of marine-sponge-derived natural products.

Authors:  Tyler A Johnson; Micaela V C Morgan; Natalie A Aratow; Samarkand A Estee; Koneni V Sashidhara; Steven T Loveridge; Nathaniel L Segraves; Phillip Crews
Journal:  J Nat Prod       Date:  2010-03-26       Impact factor: 4.050

10.  New classes of environmental tumor promoters: indole alkaloids and polyacetates.

Authors:  H Fujiki; T Sugimura; R E Moore
Journal:  Environ Health Perspect       Date:  1983-04       Impact factor: 9.031
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