Literature DB >> 21030245

Biologically active secondary metabolites from marine cyanobacteria.

Joshawna K Nunnery1, Emily Mevers, William H Gerwick.   

Abstract

Marine cyanobacteria are a rich source of complex bioactive secondary metabolites which derive from mixed biosynthetic pathways. Recently, several marine cyanobacterial natural products have garnered much attention due to their intriguing structures and exciting anti-proliferative or cancer cell toxic activities. Several other recently discovered secondary metabolites exhibit insightful neurotoxic activities whereas others are showing pronounced anti-inflammatory activity. A number of anti-infective compounds displaying activity against neglected diseases have also been identified, which include viridamides A and B, gallinamide A, dragonamide E, and the almiramides.
Copyright © 2010. Published by Elsevier Ltd.

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Year:  2010        PMID: 21030245      PMCID: PMC3034308          DOI: 10.1016/j.copbio.2010.09.019

Source DB:  PubMed          Journal:  Curr Opin Biotechnol        ISSN: 0958-1669            Impact factor:   9.740


  42 in total

1.  Marine Natural Products as Inhibitors of Hypoxic Signaling in Tumors.

Authors:  Dale G Nagle; Yu-Dong Zhou
Journal:  Phytochem Rev       Date:  2009-06       Impact factor: 5.374

2.  Malyngamide 2, an oxidized lipopeptide with nitric oxide inhibiting activity from a Papua New Guinea marine cyanobacterium.

Authors:  Karla L Malloy; Francisco A Villa; Niclas Engene; Teatulohi Matainaho; Lena Gerwick; William H Gerwick
Journal:  J Nat Prod       Date:  2010-12-14       Impact factor: 4.050

3.  Selective MyD88-dependent pathway inhibition by the cyanobacterial natural product malyngamide F acetate.

Authors:  Francisco A Villa; Kelly Lieske; Lena Gerwick
Journal:  Eur J Pharmacol       Date:  2009-12-16       Impact factor: 4.432

Review 4.  Cyanobacterial cyclopeptides as lead compounds to novel targeted cancer drugs.

Authors:  Ioannis Sainis; Demosthenes Fokas; Katerina Vareli; Andreas G Tzakos; Valentinos Kounnis; Evangelos Briasoulis
Journal:  Mar Drugs       Date:  2010-03-15       Impact factor: 5.118

5.  Stereospecific total synthesis of somocystinamide A.

Authors:  Takashi L Suyama; William H Gerwick
Journal:  Org Lett       Date:  2008-09-13       Impact factor: 6.005

6.  Hoiamide a, a sodium channel activator of unusual architecture from a consortium of two papua new Guinea cyanobacteria.

Authors:  Alban Pereira; Zhengyu Cao; Thomas F Murray; William H Gerwick
Journal:  Chem Biol       Date:  2009-08-28

7.  Structural and synthetic investigations of tanikolide dimer, a SIRT2 selective inhibitor, and tanikolide seco-acid from the Madagascar marine cyanobacterium Lyngbya majuscula.

Authors:  Marcelino Gutiérrez; Eric H Andrianasolo; Won Kyo Shin; Douglas E Goeger; Alexandre Yokochi; Jörg Schemies; Manfred Jung; Dennis France; Susan Cornell-Kennon; Eun Lee; William H Gerwick
Journal:  J Org Chem       Date:  2009-08-07       Impact factor: 4.354

8.  Viridamides A and B, lipodepsipeptides with antiprotozoal activity from the marine cyanobacterium Oscillatoria nigro-viridis.

Authors:  T Luke Simmons; Niclas Engene; Luis David Ureña; Luz I Romero; Eduardo Ortega-Barría; Lena Gerwick; William H Gerwick
Journal:  J Nat Prod       Date:  2008-08-21       Impact factor: 4.050

9.  Dragonamide E, a modified linear lipopeptide from Lyngbya majuscula with antileishmanial activity.

Authors:  Marcy J Balunas; Roger G Linington; Kevin Tidgewell; Amanda M Fenner; Luis-David Ureña; Gina Della Togna; Dennis E Kyle; William H Gerwick
Journal:  J Nat Prod       Date:  2010-01       Impact factor: 4.050

10.  Antillatoxin is a sodium channel activator that displays unique efficacy in heterologously expressed rNav1.2, rNav1.4 and rNav1.5 α subunits.

Authors:  Zhengyu Cao; William H Gerwick; Thomas F Murray
Journal:  BMC Neurosci       Date:  2010-12-14       Impact factor: 3.288

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  48 in total

Review 1.  Antagonistic interactions mediated by marine bacteria: the role of small molecules.

Authors:  Matthias Wietz; Katherine Duncan; Nastassia V Patin; Paul R Jensen
Journal:  J Chem Ecol       Date:  2013-07-14       Impact factor: 2.626

Review 2.  The phosphopantetheinyl transferases: catalysis of a post-translational modification crucial for life.

Authors:  Joris Beld; Eva C Sonnenschein; Christopher R Vickery; Joseph P Noel; Michael D Burkart
Journal:  Nat Prod Rep       Date:  2014-01       Impact factor: 13.423

3.  Phylogenetic inferences reveal a large extent of novel biodiversity in chemically rich tropical marine cyanobacteria.

Authors:  Niclas Engene; Sarath P Gunasekera; William H Gerwick; Valerie J Paul
Journal:  Appl Environ Microbiol       Date:  2013-01-11       Impact factor: 4.792

4.  Cytotoxic veraguamides, alkynyl bromide-containing cyclic depsipeptides from the marine cyanobacterium cf. Oscillatoria margaritifera.

Authors:  Emily Mevers; Wei-Ting Liu; Niclas Engene; Hosein Mohimani; Tara Byrum; Pavel A Pevzner; Pieter C Dorrestein; Carmenza Spadafora; William H Gerwick
Journal:  J Nat Prod       Date:  2011-04-13       Impact factor: 4.050

5.  Veraguamides A-G, cyclic hexadepsipeptides from a dolastatin 16-producing cyanobacterium Symploca cf. hydnoides from Guam.

Authors:  Lilibeth A Salvador; Jason S Biggs; Valerie J Paul; Hendrik Luesch
Journal:  J Nat Prod       Date:  2011-03-29       Impact factor: 4.050

6.  Antimicrobial activity and bioactive profiling of heterocytous cyanobacterial strains using MS/MS-based molecular networking.

Authors:  Kumar Saurav; Markéta Macho; Andreja Kust; Kateřina Delawská; Jan Hájek; Pavel Hrouzek
Journal:  Folia Microbiol (Praha)       Date:  2019-08-05       Impact factor: 2.099

7.  Parguerene and precarriebowmide, two classes of lipopeptides from the marine cyanobacterium Moorea producens.

Authors:  Emily Mevers; Tara Byrum; William H Gerwick
Journal:  J Nat Prod       Date:  2013-09-17       Impact factor: 4.050

8.  Lyngbyabellins K-N from Two Palmyra Atoll Collections of the Marine Cyanobacterium Moorea bouillonii.

Authors:  Hyukjae Choi; Emily Mevers; Tara Byrum; Frederick A Valeriote; William H Gerwick
Journal:  European J Org Chem       Date:  2012-08-14

9.  Caldora penicillata gen. nov., comb. nov. (cyanobacteria), a pantropical marine species with biomedical relevance.

Authors:  Niclas Engene; Ana Tronholm; Lilibeth A Salvador-Reyes; Hendrik Luesch; Valerie J Paul
Journal:  J Phycol       Date:  2015-08       Impact factor: 2.923

10.  The marine cyanobacterial metabolite gallinamide A is a potent and selective inhibitor of human cathepsin L.

Authors:  Bailey Miller; Aaron J Friedman; Hyukjae Choi; James Hogan; J Andrew McCammon; Vivian Hook; William H Gerwick
Journal:  J Nat Prod       Date:  2013-12-23       Impact factor: 4.050

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