Literature DB >> 4022761

Determination of the stability of tetracycline suspensions by high performance liquid chromatography.

A Grobben-Verpoorten, K Dihuidi, E Roets, J Hoogmartens, H Vanderhaeghe.   

Abstract

High performance liquid chromatography was used to examine the stability of tetracycline suspensions, prepared according to the Formulary of the Dutch Pharmacists and the National Formulary v (Belgium). The influence of the nature of the buffer salt, of the pH, and of the temperature and time of storage are discussed. At slightly acid pH (4 to 5.5) and at room temperature suspensions are stable for at least three months.

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Year:  1985        PMID： 4022761     DOI： 10.1007/bf01968711

Source DB:  PubMed          Journal:  Pharm Weekbl Sci        ISSN： 0167-6555


  11 in total

1.  SOME OBSERVATIONS ON THE KINETICS OF THE C.4 EPIMERIZATION OF TETRACYCLINE.

Authors:  E G REMMERS; G M SIEGER; A P DOERSCHUK
Journal:  J Pharm Sci       Date:  1963-08       Impact factor: 3.534

2.  Solubility of antibiotics in twenty-four solvents: use in analysis.

Authors:  P J WEISS; M L ANDREW; W W WRIGHT
Journal:  Antibiot Chemother (Northfield)       Date:  1957-07

3.  Quatrimycin; preparation and properties.

Authors:  M A KAPLAN; A P GRANATEK; F H BUCKWALTER
Journal:  Antibiot Chemother (Northfield)       Date:  1957-11

4.  Kinetics of concomitant degradation of tetracycline to epitetracycline, anhydrotetracycline, and epianhydrotetracycline in acid phosphate solution.

Authors:  P H Yuen; T D Sokoloski
Journal:  J Pharm Sci       Date:  1977-11       Impact factor: 3.534

5.  Aspects of the epimerization of certain tetracycline derivatives.

Authors:  D A Hussar; P J Niebergall; E T Sugita; J T Doluisio
Journal:  J Pharm Pharmacol       Date:  1968-07       Impact factor: 3.765

6.  Kinetics of dehydration of epitetracycline in solution.

Authors:  B A Hoener; T D Sokoloski; L A Mitscher; L Malspeis
Journal:  J Pharm Sci       Date:  1974-12       Impact factor: 3.534

7.  Effect of solubilizers on the stability of tetracycline.

Authors:  V Naggar; N A Daabis; M M Motawi
Journal:  Pharmazie       Date:  1974-02       Impact factor: 1.267

8.  [Study of the stability in methanolic solution of tetracycline hydrochloride and some analogues (author's transl)].

Authors:  K Dihuidi; E Roets; J Hoogmartens; H Vanderhaeghe
Journal:  J Pharm Belg       Date:  1982 Jan-Feb

9.  Rate and proposed mechanism of anhydrotetracycline epimerization in acid solution.

Authors:  T D Sokoloski; L A Mitscher; P H Yuen; J V Juvarkar; B Hoener
Journal:  J Pharm Sci       Date:  1977-08       Impact factor: 3.534

10.  Dehydration of tetracycline.

Authors:  K D Schlecht; C W Frank
Journal:  J Pharm Sci       Date:  1975-02       Impact factor: 3.534
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