Literature DB >> 1127597

Dehydration of tetracycline.

K D Schlecht, C W Frank.   

Abstract

The dehydration of tetracycline at the C-5a-C-6 position as a function of acidity was investigated at various temperatures. The rate was first order with respect to tetracycline and with respect to [H+]. Rate constants and an activation energy are reported. Tetracycline was unstable in dilute acid.

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Year:  1975        PMID： 1127597     DOI： 10.1002/jps.2600640241

Source DB:  PubMed          Journal:  J Pharm Sci        ISSN： 0022-3549            Impact factor:   3.534


  4 in total

1.  Isolation of pure anhydrotetracycline oxygenase from Streptomyces aureofaciens.

Authors:  I Vancurová; J Volc; M Flieger; J Neuzil; J Novotná; J Vlach; V Bĕhal
Journal:  Biochem J       Date:  1988-07-01       Impact factor: 3.857

2.  Determination of the stability of tetracycline suspensions by high performance liquid chromatography.

Authors:  A Grobben-Verpoorten; K Dihuidi; E Roets; J Hoogmartens; H Vanderhaeghe
Journal:  Pharm Weekbl Sci       Date:  1985-06-21

3.  pH-dependent spectroscopy of tetracycline and its analogs.

Authors:  Elmer-Rico E Mojica; Eric Nguyen; Mariya Rozov; Frank V Bright
Journal:  J Fluoresc       Date:  2014-05-09       Impact factor: 2.217

4.  Rapid Raman Spectroscopic Analysis of Stress Induced Degradation of the Pharmaceutical Drug Tetracycline.

Authors:  Domes Christian; Frosch Timea; Popp Juergen; Torsten Frosch
Journal:  Molecules       Date:  2020-04-17       Impact factor: 4.411
  4 in total

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