Literature DB >> 4015078

Effects of general and local anesthesia on the pharmacokinetics of cefazolin in patients undergoing orthopedic surgery.

W D Welch, J P Jantzen, K Johnson, R E Bawdon.   

Abstract

The pharmacokinetics of cefazolin in patients undergoing orthopedic surgery with either general (enflurane) or local (lidocaine or marcaine) anesthesia were studied. No differences in either mean serum levels at 30, 60, or 120 min after the intravenous injection of cefazolin or serum half-lives were seen between the two groups of patients.

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Year:  1985        PMID： 4015078      PMCID： PMC180170          DOI： 10.1128/AAC.27.5.874

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  7 in total

1.  Pharmacokinetic interpretation of blood levels and urinary excretion data for cefazolin and cephalothin after intravenous and intramuscular administration in humans.

Authors:  E S Rattie; L J Ravin
Journal:  Antimicrob Agents Chemother       Date:  1975-05       Impact factor: 5.191

2.  Changes in pharmacokinetics of cefazolin due to stress.

Authors:  C H Nightingale; H Bassaris; R Tilton; R Quintiliani
Journal:  J Pharm Sci       Date:  1975-04       Impact factor: 3.534

3.  The penetration characteristics of cefazolin, cephalothin, and cephradine into bone in patients undergoing total hip replacement.

Authors:  B A Cunha; H R Gossling; H S Pasternak; C H Nightingale; R Quintiliani
Journal:  J Bone Joint Surg Am       Date:  1977-10       Impact factor: 5.284

4.  Pharmacology of cefazolin in human volunteers.

Authors:  P Nicholas; B R Meyers; S Z Hirschman
Journal:  J Clin Pharmacol       Date:  1973 Aug-Sep       Impact factor: 3.126

5.  Penetration of cephalosporins into bone.

Authors:  B A Cunha; H R Gossling; H S Pasternak; C H Nightingale; R Quintiliani
Journal:  Infection       Date:  1984 Mar-Apr       Impact factor: 3.553

6.  Evaluation of cefazolin, a new cephalosporin antibiotic.

Authors:  L B Reller; W W Karney; H N Beaty; K K Holmes; M Turck
Journal:  Antimicrob Agents Chemother       Date:  1973-04       Impact factor: 5.191

7.  Moxalactam and cefazolin: comparative pharmacokinetics in normal subjects.

Authors:  W M Scheld; D A Spyker; G R Donowitz; W K Bolton; M A Sande
Journal:  Antimicrob Agents Chemother       Date:  1981-04       Impact factor: 5.191
  7 in total
  2 in total

1.  Pharmacokinetics and protein binding of cefazolin in morbidly obese patients.

Authors:  Simone van Kralingen; Margot Taks; Jeroen Diepstraten; Ewoudt M van de Garde; Eric P van Dongen; Marinus J Wiezer; Bert van Ramshorst; Bart Vlaminckx; Vera H Deneer; Catherijne A Knibbe
Journal:  Eur J Clin Pharmacol       Date:  2011-04-16       Impact factor: 2.953

2.  Cationic antimicrobial peptide LL-37 is effective against both extra- and intracellular Staphylococcus aureus.

Authors:  Jabeen Noore; Adly Noore; Bingyun Li
Journal:  Antimicrob Agents Chemother       Date:  2012-12-28       Impact factor: 5.191
  2 in total

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