Literature DB >> 4010699

A human cell line sensitive to mutation by particle-borne chemicals.

C L Crespi, H L Liber, T D Behymer, R A Hites, W G Thilly.   

Abstract

A human lymphoblastoid cell line with ability to perform oxidative metabolism of various chemicals is mutated by the direct addition of an intact particulate soot. This experiment demonstrates that materials associated with combustion-generated particulates are biologically available and able to cause genetic changes in metabolically competent human cells.

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Year:  1985        PMID: 4010699     DOI: 10.1016/0165-1218(85)90051-5

Source DB:  PubMed          Journal:  Mutat Res        ISSN: 0027-5107            Impact factor:   2.433


  2 in total

1.  Mutagenic activity of Mintostachys mollis in AHH1 lymphoblast cells.

Authors:  G Carvajal; W Thilly
Journal:  Plant Foods Hum Nutr       Date:  1988       Impact factor: 3.921

2.  Assay of mutation induced in human lymphoblastoid cells by combustion-generated soot particles.

Authors:  P P Bolsaitis; A S Feitelberg; V Dekermendjian; J F Elliott; A F Sarofim; W G Thilly
Journal:  Environ Health Perspect       Date:  1991-12       Impact factor: 9.031

  2 in total

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