| Literature DB >> 400957 |
W S Davidson1, D J Walton, T G Flynn.
Abstract
1. NADPH-dependent aldehyde reductase (AR) is widely distributed among animal species. It also occurs in flowering plants and fungi (yeast). 2. AR is located mainly in the kidney or renal tissue of all species examined, with the exception of fish where it occurs mainly in the liver. 3. The enzyme from each species is monomeric and has a molecular weight between 30,000 and 40,000 daltons. 4. The enzymes exhibit similar substrate specificities and pH profiles and are inhibited by barbiturates. 5. In the reduction of D-glyceraldehyde the monomeric AR of each species catalyzes the stereospecific transfer of the A hydrogen from NADPH.Entities:
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Year: 1978 PMID： 400957 DOI： 10.1016/0305-0491(78)90106-2
Source DB: PubMed Journal: Comp Biochem Physiol B ISSN： 0305-0491