Literature DB >> 4007605

Ketoconazole-induced fulminant hepatitis.

E Bercoff, J Bernuau, C Degott, B Kalis, A Lemaire, H Tilly, B Rueff, J P Benhamou.   

Abstract

We report the cases of two adult patients in whom fulminant hepatitis developed after 17 and 103 days of ketoconazole administration. Histologic administration showed massive, predominantly centrilobular necrosis. Clinical manifestations of hypersensitivity and eosinophilia were absent in both patients, which suggests that ketoconazole hepatotoxicity is not mediated through an immunoallergic mechanism.

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Year:  1985        PMID： 4007605      PMCID： PMC1432772          DOI： 10.1136/gut.26.6.636

Source DB:  PubMed          Journal:  Gut        ISSN： 0017-5749            Impact factor:   23.059


  11 in total

1.  RENAL AND POSSIBLY HEPATIC TOXICITY FROM COLY-MYCIN. REPORT OF A CASE.

Authors:  R KATZ
Journal:  Med Ann Dist Columbia       Date:  1963-10

2.  Toxic hepatis during ketoconazole treatment.

Authors:  J K Heiberg; E Svejgaard
Journal:  Br Med J (Clin Res Ed)       Date:  1981-09-26

3.  Hepatitis and ketoconazole therapy.

Authors: 
Journal:  Br Med J (Clin Res Ed)       Date:  1981-10-17

4.  Hepatic dysfunction and ketoconazole therapy.

Authors:  E Svejgaard; L Ranek
Journal:  Ann Intern Med       Date:  1982-06       Impact factor: 25.391

5.  Transvenous liver biopsy: an experience based on 1000 hepatic tissue samplings with this procedure.

Authors:  D Lebrec; G Goldfarb; C Degott; B Rueff; J P Benhamou
Journal:  Gastroenterology       Date:  1982-08       Impact factor: 22.682

6.  Portal hypertension in fulminant viral hepatitis.

Authors:  D Lebrec; O Nouel; J Bernuau; B Rueff; J P Benhamou
Journal:  Gut       Date:  1980-11       Impact factor: 23.059

7.  Hepatic injury associated with ketoconazole therapy. Analysis of 33 cases.

Authors:  J H Lewis; H J Zimmerman; G D Benson; K G Ishak
Journal:  Gastroenterology       Date:  1984-03       Impact factor: 22.682

8.  Successful ketoconazole treatment of protothecosis with ketoconazole-associated hepatotoxicity.

Authors:  P S Pegram; F T Kerns; B L Wasilauskas; K D Hampton; M Scharyj; J G Burke
Journal:  Arch Intern Med       Date:  1983-09

9.  Severe hepatitis during ketoconazole therapy.

Authors:  H Okumura; T Aramaki; K Satomura; K Iizuka; M Ohta; Y Katsuta; M Akaike; H Terada; T Kusunoki
Journal:  Gastroenterol Jpn       Date:  1983-04

Review 10.  Drug effects on the liver. An updated tabular compilation of drugs and drug-related hepatic diseases.

Authors:  J Ludwig; R Axelsen
Journal:  Dig Dis Sci       Date:  1983-07       Impact factor: 3.199
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  9 in total

Review 1.  Adverse drug reactions to systemic antifungals. Prevention and management.

Authors:  J R Perfect; M H Lindsay; R H Drew
Journal:  Drug Saf       Date:  1992 Sep-Oct       Impact factor: 5.606

2.  Prolonged jaundice following ketoconazole-induced hepatic injury.

Authors:  G D Benson; P K Anderson; B Combes; K G Ishak
Journal:  Dig Dis Sci       Date:  1988-02       Impact factor: 3.199

Review 3.  Fungal toenail infections.

Authors:  Jill Ferrari
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4.  Hepatic reactions associated with ketoconazole in the United Kingdom.

Authors:  G Lake-Bakaar; P J Scheuer; S Sherlock
Journal:  Br Med J (Clin Res Ed)       Date:  1987-02-14

5.  Fatal hepatitis associated with diclofenac.

Authors:  E G Breen; J McNicholl; E Cosgrove; J McCabe; F M Stevens
Journal:  Gut       Date:  1986-11       Impact factor: 23.059

6.  Hepatic safety of voriconazole after allogeneic hematopoietic stem cell transplantation.

Authors:  I Amigues; N Cohen; D Chung; S K Seo; C Plescia; A Jakubowski; J Barker; Genovefa A Papanicolaou
Journal:  Biol Blood Marrow Transplant       Date:  2009-10-09       Impact factor: 5.742

7.  Esophageal candidiasis in AIDS. Successful therapy with clotrimazole vaginal tablets taken by mouth.

Authors:  E Lalor; L Rabeneck
Journal:  Dig Dis Sci       Date:  1991-03       Impact factor: 3.199

Review 8.  The treatment of advanced prostate cancer with ketoconazole: safety issues.

Authors:  R A Bok; E J Small
Journal:  Drug Saf       Date:  1999-05       Impact factor: 5.228

9.  Enantiospecific effects of ketoconazole on aryl hydrocarbon receptor.

Authors:  Aneta Novotna; Martina Korhonova; Iveta Bartonkova; Anatoly A Soshilov; Michael S Denison; Katerina Bogdanova; Milan Kolar; Petr Bednar; Zdenek Dvorak
Journal:  PLoS One       Date:  2014-07-07       Impact factor: 3.240
  9 in total

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