Literature DB >> 3792922

Fatal hepatitis associated with diclofenac.

E G Breen, J McNicholl, E Cosgrove, J McCabe, F M Stevens.   

Abstract

Non-steroidal anti-inflammatory agents (NSAIDS) are a well recognised cause of hepatotoxicity. Diclofenac, a relatively new NSAID, was first introduced into the UK in 1979. Five cases of hepatitis have recently been reported, principally in the French literature. We report the first fulminant case of hepatitis in the English literature in a patient taking diclofenac and indomethacin.

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Year:  1986        PMID: 3792922      PMCID: PMC1434053          DOI: 10.1136/gut.27.11.1390

Source DB:  PubMed          Journal:  Gut        ISSN: 0017-5749            Impact factor:   23.059


  17 in total

1.  Stevens-Johnson syndrome plus toxic hepatitis due to ibuprofen.

Authors:  P Sternlieb; R M Robinson
Journal:  N Y State J Med       Date:  1978-07

2.  Jaundice associated with the use of benoxaprofen.

Authors:  B M Goudie; G F Birnie; G Watkinson; R N MacSween; L H Kissen; N E Cunningham
Journal:  Lancet       Date:  1982-04-24       Impact factor: 79.321

3.  [Pirprofen hepatitis with a favorable development. Apropos of 5 cases].

Authors:  A Castot; P Netter; J P Arnaudo; J Andrieu; F Vicari; B Ponge; J M Wilhelm; G Danan; P Trechot; J H Frelon
Journal:  Therapie       Date:  1984 May-Jun       Impact factor: 2.070

4.  [Diclofenac hepatitis. A case].

Authors:  P Deshayes; X Leloet; E Bercoff; H Fouin-Fortunet
Journal:  Presse Med       Date:  1984 Sep 1-8       Impact factor: 1.228

5.  Diclofenac hepatitis.

Authors:  A A Dunk; R P Walt; W J Jenkins; S S Sherlock
Journal:  Br Med J (Clin Res Ed)       Date:  1982-05-29

6.  [Hepatitis caused by diclofenac].

Authors:  G Babany; D Pessayre; J P Benhamou
Journal:  Gastroenterol Clin Biol       Date:  1983-03

7.  Fatal hepatitis probably due to indomethacin.

Authors:  W M Kelsey; M Scharyj
Journal:  JAMA       Date:  1967-02-20       Impact factor: 56.272

8.  The destruction of cytochrome P-450 by alclofenac: possible involvement of an epoxide metabolite.

Authors:  L M Brown; A W Ford-Hutchinson
Journal:  Biochem Pharmacol       Date:  1982-01-15       Impact factor: 5.858

9.  Report on a long-term tolerability study of up to two years with diclofenac sodium (Voltaren).

Authors:  S N Ciccolunghi; H A Chaudri; B I Schubiger; R Reddrop
Journal:  Scand J Rheumatol Suppl       Date:  1978

10.  IBUFENAC (4-ISOBUTYLPHENYL ACETIC ACID).

Authors:  F D HART; P L BOARDMAN
Journal:  Ann Rheum Dis       Date:  1965-01       Impact factor: 19.103

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  12 in total

1.  Renal and hepatic impairment in association with diclofenac administration.

Authors:  P Diggory; R L Golding; R Lancaster
Journal:  Postgrad Med J       Date:  1989-07       Impact factor: 2.401

2.  Azapropazone induced hepatitis.

Authors:  T C Lo; I W Dymock
Journal:  BMJ       Date:  1988-12-17

Review 3.  Drug-induced "allergic hepatitis".

Authors:  P Podevin; M Biour
Journal:  Clin Rev Allergy Immunol       Date:  1995       Impact factor: 8.667

Review 4.  Immunological principles of adverse drug reactions: the initiation and propagation of immune responses elicited by drug treatment.

Authors:  D J Naisbitt; S F Gordon; M Pirmohamed; B K Park
Journal:  Drug Saf       Date:  2000-12       Impact factor: 5.606

Review 5.  Nonsteroidal anti-inflammatory drug-induced hepatic disorders. Incidence and prevention.

Authors:  A V Manoukian; J L Carson
Journal:  Drug Saf       Date:  1996-07       Impact factor: 5.606

Review 6.  Diclofenac induced hepatitis. 3 cases with features of autoimmune chronic active hepatitis.

Authors:  L J Scully; D Clarke; R J Barr
Journal:  Dig Dis Sci       Date:  1993-04       Impact factor: 3.199

7.  Diclofenac hepatitis.

Authors:  P Purcell; D Henry; G Melville
Journal:  Gut       Date:  1991-11       Impact factor: 23.059

Review 8.  Diclofenac sodium. A reappraisal of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy.

Authors:  P A Todd; E M Sorkin
Journal:  Drugs       Date:  1988-03       Impact factor: 9.546

9.  Piroxicam induced submassive necrosis of the liver.

Authors:  D Paterson; P Kerlin; N Walker; S Lynch; R Strong
Journal:  Gut       Date:  1992-10       Impact factor: 23.059

10.  Grand rounds: an outbreak of toxic hepatitis among industrial waste disposal workers.

Authors:  Hae-Kwan Cheong; Eun A Kim; Jung-Keun Choi; Sung-Bong Choi; Jeong-Ill Suh; Dae Seob Choi; Jung Ran Kim
Journal:  Environ Health Perspect       Date:  2007-01       Impact factor: 9.031

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