Literature DB >> 4000275

Quaternary structure of the acetylcholine receptor.

A Brisson, P N Unwin.   

Abstract

The five membrane-spanning subunits of the acetylcholine receptor have been resolved in electron microscope images and are shown to lie at pentagonally symmetrical positions around the channel over a large fraction of their length. The channel consists of a wide synaptic portion and a narrow portion extending through the membrane into the interior of the cell.

Mesh：

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Year:  1985        PMID： 4000275     DOI： 10.1038/315474a0

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


  59 in total

1.  alpha4beta2 Nicotinic acetylcholine receptors, willing if able.

Authors:  Roger L Papke
Journal:  Br J Pharmacol       Date:  2010-08       Impact factor: 8.739

Review 2.  Structural analysis of mitochondrial pores.

Authors:  C A Mannella
Journal:  Experientia       Date:  1990-02-15

Review 3.  Structure and function of channels and channelogs as studied by computational chemistry.

Authors:  G Eisenman; O Alvarez
Journal:  J Membr Biol       Date:  1991-01       Impact factor: 1.843

Review 4.  The concept of allosteric interaction and its consequences for the chemistry of the brain.

Authors:  Jean-Pierre Changeux
Journal:  J Biol Chem       Date:  2013-07-22       Impact factor: 5.157

5.  Ion-channel entrances influence permeation. Net charge, size, shape, and binding considerations.

Authors:  J A Dani
Journal:  Biophys J       Date:  1986-03       Impact factor: 4.033

Review 6.  Orthosteric and allosteric potentiation of heteromeric neuronal nicotinic acetylcholine receptors.

Authors:  Jingyi Wang; Jon Lindstrom
Journal:  Br J Pharmacol       Date:  2017-03-20       Impact factor: 8.739

7.  Atomic force microscopy of cloned nicotinic acetylcholine receptor expressed in Xenopus oocytes.

Authors:  R Lal; L Yu
Journal:  Proc Natl Acad Sci U S A       Date:  1993-08-01       Impact factor: 11.205

Review 8.  The main immunogenic region (MIR) of the nicotinic acetylcholine receptor and the anti-MIR antibodies.

Authors:  S J Tzartos; M T Cung; P Demange; H Loutrari; A Mamalaki; M Marraud; I Papadouli; C Sakarellos; V Tsikaris
Journal:  Mol Neurobiol       Date:  1991       Impact factor: 5.590

9.  A single historical substitution drives an increase in acetylcholine receptor complexity.

Authors:  Johnathon R Emlaw; Christian J G Tessier; Gregory D McCluskey; Melissa S McNulty; Yusuf Sheikh; Kelly M Burkett; Maria Musgaard; Corrie J B daCosta
Journal:  Proc Natl Acad Sci U S A       Date:  2021-02-16       Impact factor: 11.205

10.  Allosteric binding site in a Cys-loop receptor ligand-binding domain unveiled in the crystal structure of ELIC in complex with chlorpromazine.

Authors:  Mieke Nys; Eveline Wijckmans; Ana Farinha; Özge Yoluk; Magnus Andersson; Marijke Brams; Radovan Spurny; Steve Peigneur; Jan Tytgat; Erik Lindahl; Chris Ulens
Journal:  Proc Natl Acad Sci U S A       Date:  2016-10-10       Impact factor: 11.205
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