Literature DB >> 3996465

Attenuation of the baroreceptor reflex by general anesthetic agents in the normotensive rat.

J P Fluckiger, M Sonnay, N Boillat, J Atkinson.   

Abstract

We have investigated the effects of urethane, a urethane + allobarbital mixture, alpha-chloralose and sodium pentobarbital on baroreceptor reflex function in the normotensive rat. Results were compared to those obtained in the conscious rat. Baroreceptor reflex function was evaluated from the fall in heart rate which accompanied the rise in diastolic arterial pressure following intravenous administration of phenylephrine. All four anesthetic agents attenuated reflex function as shown by a decrease in the bradycardiac response. There was a four to five-fold attenuation with urethane and urethane + allobarbital and a two- to three-fold attenuation with alpha-chloralose and sodium pentobarbital.

Entities:  

Mesh：

Substances：

Year:  1985        PMID： 3996465     DOI： 10.1016/0014-2999(85)90545-x

Source DB:  PubMed          Journal:  Eur J Pharmacol        ISSN： 0014-2999            Impact factor:   4.432


  20 in total

1.  AT2 and MAS (but not AT1) angiotensinergic receptors in the medial amygdaloid nucleus modulate the baroreflex activity in rats.

Authors:  Willian Costa-Ferreira; Lucas Gomes-de-Souza; Carlos C Crestani
Journal:  Pflugers Arch       Date:  2019-08-08       Impact factor: 3.657

2.  Cardiovascular effects of two new calcium antagonists, PY 108-068 and PN 200-110, in conscious spontaneously hypertensive rats.

Authors:  C Barrès; C Cerutti; B Morin; J Sassard
Journal:  Br J Pharmacol       Date:  1988-01       Impact factor: 8.739

3.  Captopril improves cerebrovascular structure and function in old hypertensive rats.

Authors:  François Dupuis; Jeffrey Atkinson; Patrick Limiñana; Jean-Marc Chillon
Journal:  Br J Pharmacol       Date:  2005-02       Impact factor: 8.739

4.  Sympathoexcitation in ANG II-salt hypertension involves reduced SK channel function in the hypothalamic paraventricular nucleus.

Authors:  Robert A Larson; Le Gui; Michael J Huber; Andrew D Chapp; Jianhua Zhu; Lila P LaGrange; Zhiying Shan; Qing-Hui Chen
Journal:  Am J Physiol Heart Circ Physiol       Date:  2015-04-10       Impact factor: 4.733

5.  Pharmacological evidence for the activation of potassium channels as the mechanism involved in the hypotensive and vasorelaxant effect of dioclein in rat small resistance arteries.

Authors:  S F Côrtes; B A Rezende; C Corriu; I A Medeiros; M M Teixeira; M J Lopes; V S Lemos
Journal:  Br J Pharmacol       Date:  2001-07       Impact factor: 8.739

Review 6.  Suitability of urethane anesthesia for physiopharmacological investigations in various systems. Part 2: Cardiovascular system.

Authors:  C A Maggi; A Meli
Journal:  Experientia       Date:  1986-03-15

7.  Development of a decerebrate model for investigating mechanisms mediating viscero-sympathetic reflexes in the spinalized rat.

Authors:  Christian A Reynolds; Donal S O'Leary; Cheng Ly; Scott A Smith; Zeljka Minic
Journal:  Am J Physiol Heart Circ Physiol       Date:  2019-03-15       Impact factor: 4.733

8.  Strain differences in baroceptor reflex in adult Wistar Kyoto rats.

Authors:  Vitor E Valenti; Luiz Carlos de Abreu; Caio Imaizumi; Márcio Petenusso; Celso Ferreira
Journal:  Clinics (Sao Paulo)       Date:  2010-02       Impact factor: 2.365

9.  Cardiovascular responses induced by Catalase Inhibitior into the Fourth Cerebral Ventricle is changed in Wistar rats exposed to sidestream cigarette smoke.

Authors:  Vitor E Valenti; Luiz Carlos de Abreu; Fernando L A Fonseca; Jose-Luiz Figueiredo; Fernando Adami; Celso Ferreira
Journal:  Int J Health Sci (Qassim)       Date:  2013-06

10.  Role of Muscarinic Acetylcholine Receptor-2 in the Cerebellar Cortex in Cardiovascular Modulation in Anaesthetized Rats.

Authors:  Changzheng Zhang; Tingzhe Sun; Peiling Zhou; Qingfeng Zhu; Liefeng Zhang
Journal:  Neurochem Res       Date:  2015-11-02       Impact factor: 3.996
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.