Literature DB >> 3990807

Three-dimensional structure of calmodulin.

Y S Babu, J S Sack, T J Greenhough, C E Bugg, A R Means, W J Cook.   

Abstract

The three-dimensional structure of calmodulin has been determined crystallographically at 3.0 A resolution. The molecule consists of two globular lobes connected by a long exposed alpha-helix. Each lobe binds two calcium ions through helix-loop-helix domains similar to those of other calcium-binding proteins. The long helix between the lobes may be involved in interactions of calmodulin with drugs and various proteins.

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Year:  1985        PMID： 3990807     DOI： 10.1038/315037a0

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


  186 in total

1.  Cooperative folding units of escherichia coli tryptophan repressor.

Authors:  A Wallqvist; T A Lavoie; J A Chanatry; D G Covell; J Carey
Journal:  Biophys J       Date:  1999-09       Impact factor: 4.033

2.  Evolutionary relationships of Metazoa within the eukaryotes based on molecular data from Porifera.

Authors:  J Schütze; A Krasko; M R Custodio; S M Efremova; I M Müller; W E Müller
Journal:  Proc Biol Sci       Date:  1999-01-07       Impact factor: 5.349

3.  Physiological calcium concentrations regulate calmodulin binding and catalysis of adenylyl cyclase exotoxins.

Authors:  Yuequan Shen; Young-Sam Lee; Sandriyana Soelaiman; Pamela Bergson; Dan Lu; Alice Chen; Kathy Beckingham; Zenon Grabarek; Milan Mrksich; Wei-Jen Tang
Journal:  EMBO J       Date:  2002-12-16       Impact factor: 11.598

4.  Redox-Responsive Protein Design: Design of a Small Protein Motif Dependent on Glutathionylation.

Authors:  Michael J Scheuermann; Christina R Forbes; Neal J Zondlo
Journal:  Biochemistry       Date:  2018-12-13       Impact factor: 3.162

5.  Transcriptional effect of a calmodulin inhibitor, W-7, on the ligninolytic enzyme genes in Phanerochaete chrysosporium.

Authors:  Takaiku Sakamoto; Hironori Kitaura; Masahiko Minami; Yoichi Honda; Takashi Watanabe; Akio Ueda; Kazumi Suzuki; Toshikazu Irie
Journal:  Curr Genet       Date:  2010-06-09       Impact factor: 3.886

6.  Mechanism of CaM kinase IV activation during hypoxia in neuronal nuclei of the cerebral cortex of newborn piglets: the role of Src kinase.

Authors:  Maria Delivoria-Papadopoulos; Qazi M Ashraf; Om Prakash Mishra
Journal:  Neurochem Res       Date:  2011-04-23       Impact factor: 3.996

7.  The low-affinity Ca2(+)-binding sites in cardiac/slow skeletal muscle troponin C perform distinct functions: site I alone cannot trigger contraction.

Authors:  H L Sweeney; R M Brito; P R Rosevear; J A Putkey
Journal:  Proc Natl Acad Sci U S A       Date:  1990-12       Impact factor: 11.205

8.  Two distinct myosin light chain structures are induced by specific variations within the bound IQ motifs-functional implications.

Authors:  Mohammed Terrak; Guanming Wu; Walter F Stafford; Renne C Lu; Roberto Dominguez
Journal:  EMBO J       Date:  2003-02-03       Impact factor: 11.598

9.  Fluorescence intensity and lifetime distribution analysis: toward higher accuracy in fluorescence fluctuation spectroscopy.

Authors:  Kaupo Palo; Leif Brand; Christian Eggeling; Stefan Jäger; Peet Kask; Karsten Gall
Journal:  Biophys J       Date:  2002-08       Impact factor: 4.033

10.  Utilization of a calmodulin lysine methyltransferase co-expression system for the generation of a combinatorial library of post-translationally modified proteins.

Authors:  Roberta Magnani; Brian Chaffin; Emerson Dick; Michael L Bricken; Robert L Houtz; Luke H Bradley
Journal:  Protein Expr Purif       Date:  2012-10-02       Impact factor: 1.650
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