Literature DB >> 3987799

Effect of a single oral dose of doxycycline on polymorphonuclear leukocyte migration in a casein gradient.

O Bäck, B Norberg.   

Abstract

Tetracyclines, especially doxycycline, have been reported to inhibit the in vitro migration of polymorphonuclear leukocytes (PMNs). Twelve healthy probands were treated with doxycycline 200 mg. No inhibition of PMN migration in a casein gradient was demonstrated 24 h later. It is suggested that the effect of oral treatment with doxycycline on PMN chemotaxis is negligible.

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Year:  1985        PMID： 3987799     DOI： 10.1007/bf00609691

Source DB:  PubMed          Journal:  Eur J Clin Pharmacol        ISSN： 0031-6970            Impact factor:   2.953


  13 in total

1.  The difference between random movement and chemotaxis. Effects of antitubulins on neutrophil granulocyte locomotion.

Authors:  U Bandmann; L Rydgren; B Norberg
Journal:  Exp Cell Res       Date:  1974-09       Impact factor: 3.905

2.  Analysis of polymorphonuclear leukocyte (PMN) migration by the leading-front technique. Random locomotion and chemotaxis.

Authors:  U B Söderström; G Simmingsköld; B Norberg; O Bäck; L Rydgren
Journal:  Exp Cell Res       Date:  1979-07       Impact factor: 3.905

3.  Effects of tetracycline on leukotaxis.

Authors:  R R Martin; G A Warr; R B Couch; H Yeager; V Knight
Journal:  J Infect Dis       Date:  1974-02       Impact factor: 5.226

4.  Granulocyte function during prophylaxis with doxycycline.

Authors:  J Belsheim; H Gnarpe; J Löfberg
Journal:  Scand J Infect Dis       Date:  1979

5.  Joint fluid leukocytosis of patients with rheumatoid arthritis evidence for neutrophil and monocyte chemotaxis in vivo.

Authors:  B Norberg; A Bjelle; S Eriksson
Journal:  Clin Rheumatol       Date:  1983-09       Impact factor: 2.980

6.  The effect of a therapeutic doxycycline concentration on polymorphonuclear leukocyte migration in vitro.

Authors:  O Bäck; B Norberg
Journal:  Scand J Infect Dis       Date:  1984

7.  Direct chemotaxis and leucocyte-induced chemotaxis of polymorphonuclear leucocytes. Significance of complement, incubation time and chemotactic parameters in filter chamber assays.

Authors:  O Bäck; U Bandmann; B Norberg; U B Söderström
Journal:  Scand J Haematol       Date:  1978-02

8.  Effect of antibiotics on the in vitro neutrophil chemotactic response.

Authors:  J A Majeski; M A McClellan; J W Alexander
Journal:  Am Surg       Date:  1976-10       Impact factor: 0.688

9.  In vivo suppression of neutrophil chemotaxis by systemically and topically administered tetracycline.

Authors:  B E Elewski; B A Lamb; W M Sams; W R Gammon
Journal:  J Am Acad Dermatol       Date:  1983-06       Impact factor: 11.527

10.  Tetracyclines and host defense mechanisms: interference with leukocyte chemotaxis.

Authors:  J Belsheim; H Gnarpe; S Persson
Journal:  Scand J Infect Dis       Date:  1979
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