| Literature DB >> 3981522 |
A Segal-Eiras, G M Segura, J C Babini, A S Arturi, J M Fraguela, J C Marcos.
Abstract
The relationship between the effect of chloroquine treatment on circulating immune complexes in patients with rheumatoid arthritis (RA) was determined by the 125I Clq binding assay. Three groups were studied: (a) 20 patients treated daily for 6 months with chloroquine sulphate 250 mg plus prednisone 7.5 mg and nonsteroidal antiinflammatory drugs (NSAID); (b) 20 patients not taking antimalarials but treated with prednisone and NSAID; (c) 41 controls. Results suggest that chloroquine sulphate therapy induced a marked decrease of immune complexes in patients with RA, an effect not observed with treatment by prednisone and NSAID only.Entities:
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Year: 1985 PMID: 3981522
Source DB: PubMed Journal: J Rheumatol ISSN: 0315-162X Impact factor: 4.666