Literature DB >> 3981522

Effect of antimalarial treatment on circulating immune complexes in rheumatoid arthritis.

A Segal-Eiras, G M Segura, J C Babini, A S Arturi, J M Fraguela, J C Marcos.   

Abstract

The relationship between the effect of chloroquine treatment on circulating immune complexes in patients with rheumatoid arthritis (RA) was determined by the 125I Clq binding assay. Three groups were studied: (a) 20 patients treated daily for 6 months with chloroquine sulphate 250 mg plus prednisone 7.5 mg and nonsteroidal antiinflammatory drugs (NSAID); (b) 20 patients not taking antimalarials but treated with prednisone and NSAID; (c) 41 controls. Results suggest that chloroquine sulphate therapy induced a marked decrease of immune complexes in patients with RA, an effect not observed with treatment by prednisone and NSAID only.

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Year:  1985        PMID: 3981522

Source DB:  PubMed          Journal:  J Rheumatol        ISSN: 0315-162X            Impact factor:   4.666


  3 in total

Review 1.  Use of hydroxychloroquine to prevent thrombosis in systemic lupus erythematosus and in antiphospholipid antibody-positive patients.

Authors:  Michelle Petri
Journal:  Curr Rheumatol Rep       Date:  2011-02       Impact factor: 4.592

2.  Cellular and urinary microRNA alterations in NZB/W mice with hydroxychloroquine or prednisone treatment.

Authors:  Cristen B Chafin; Nicole L Regna; Sarah E Hammond; Christopher M Reilly
Journal:  Int Immunopharmacol       Date:  2013-10-09       Impact factor: 4.932

Review 3.  Hydroxychloroquine in systemic lupus erythematosus: overview of current knowledge.

Authors:  Alina Dima; Ciprian Jurcut; François Chasset; Renaud Felten; Laurent Arnaud
Journal:  Ther Adv Musculoskelet Dis       Date:  2022-02-14       Impact factor: 5.346

  3 in total

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