Literature DB >> 3977885

2-Chloroadenosine inhibits complement-induced reactive oxygen metabolite production and recovery of human polymorphonuclear leucocytes attacked by complement.

P A Roberts, B P Morgan, A K Campbell.   

Abstract

Luminol-enhanced chemiluminescence demonstrated that 2-chloroadenosine inhibited complement-induced reactive oxygen metabolite production in human polymorphonuclear leucocytes. This inhibition was reversed by 8-phenyltheophylline. Binding of a [125I]-labelled monoclonal antibody against C9 to human PMN demonstrated removal of membrane attack complexes from the cell membranes, and in addition indicated inhibition of this process by 2-chloroadenosine. This compound also increased the percentage of complement-induced cell lysis of polymorphonuclear leucocytes.

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Year:  1985        PMID： 3977885     DOI： 10.1016/0006-291x(85)90240-2

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


  11 in total

Review 1.  Molecular mechanism of methotrexate action in inflammation.

Authors:  B N Cronstein
Journal:  Inflammation       Date:  1992-10       Impact factor: 4.092

Review 2.  The role of neutrophils in vascular injury: a summary of signal transduction mechanisms in cell/cell interactions.

Authors:  G Weissmann
Journal:  Springer Semin Immunopathol       Date:  1989

Review 3.  Complement membrane attack on nucleated cells: resistance, recovery and non-lethal effects.

Authors:  B P Morgan
Journal:  Biochem J       Date:  1989-11-15       Impact factor: 3.857

Review 4.  Adenosine and adenosine receptors in the pathogenesis and treatment of rheumatic diseases.

Authors:  Bruce N Cronstein; Michail Sitkovsky
Journal:  Nat Rev Rheumatol       Date:  2016-11-10       Impact factor: 20.543

5.  The membrane attack complex of complement induces permeability changes via thresholds in individual cells.

Authors:  A K Patel; A K Campbell
Journal:  Immunology       Date:  1987-01       Impact factor: 7.397

6.  Suppression of human polymorphonuclear leukocyte phagocytosis by adenosine analogs.

Authors:  Y Nishida; Z Honda; T Miyamoto
Journal:  Inflammation       Date:  1987-09       Impact factor: 4.092

Review 7.  Membrane signaling by complement C5b-9, the membrane attack complex.

Authors:  A Nicholson-Weller; J A Halperin
Journal:  Immunol Res       Date:  1993       Impact factor: 2.829

8.  The recovery of human polymorphonuclear leucocytes from sublytic complement attack is mediated by changes in intracellular free calcium.

Authors:  B P Morgan; A K Campbell
Journal:  Biochem J       Date:  1985-10-01       Impact factor: 3.857

9.  Detection of membrane-bound and soluble antigens by magnetic levitation.

Authors:  Mikkel Schou Andersen; Emily Howard; Shulin Lu; Matthew Richard; Mark Gregory; Gordon Ogembo; Ofer Mazor; Pavel Gorelik; Nathan I Shapiro; Anish V Sharda; Ionita Ghiran
Journal:  Lab Chip       Date:  2017-10-11       Impact factor: 6.799

10.  Rapid activation of monocyte tissue factor by antithymocyte globulin is dependent on complement and protein disulfide isomerase.

Authors:  Florian Langer; Brigitte Spath; Cornelia Fischer; Moritz Stolz; Francis A Ayuk; Nicolaus Kröger; Carsten Bokemeyer; Wolfram Ruf
Journal:  Blood       Date:  2013-01-11       Impact factor: 22.113
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