Literature DB >> 3970956

Characterization of two molecular species GD3 ganglioside from bovine buttermilk.

B Hauttecoeur, S Sonnino, R Ghidoni.   

Abstract

Two gangliosides, representing 85% of total lipid-bound sialic acid, have been isolated from bovine buttermilk and characterized. Both contained long-chain base, glucose, galactose and sialic acid in the molar ratio 1:1:1:2, and gave, upon sialidase treatment, a neutral glycolipid, characterized as lactosylceramide. Partial acid hydrolysis, permethylation analysis and chromium trioxide oxidation indicated their basic oligosaccharide portion to be NeuAc alpha 2----8NeuAc alpha 2----3Gal beta 1----4Glc. The difference between the two forms was exclusively in the ceramide moiety of the molecule, one containing mainly long-chain (C22-C25) fatty acids and an equimolar proportion of C16 and C18 long-chain bases, and the other mainly palmitic acid and C18 long-chain base.

Entities:  

Mesh：

Substances：

Year:  1985        PMID： 3970956     DOI： 10.1016/0005-2760(85)90202-4

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN： 0006-3002


  8 in total

1.  Sialic acid glycoproteins inhibit in vitro and in vivo replication of rotaviruses.

Authors:  R H Yolken; R Willoughby; S B Wee; R Miskuff; S Vonderfecht
Journal:  J Clin Invest       Date:  1987-01       Impact factor: 14.808

2.  Bovine milk gangliosides: changes in ceramide moiety with stage of lactation.

Authors:  M J Martín; S Martín-Sosa; P Hueso
Journal:  Lipids       Date:  2001-03       Impact factor: 1.880

3.  Characterization of the ganglioside recognition profile of Escherichia coli heat-labile enterotoxin LT-IIc.

Authors:  Dani Zalem; Martin Juhás; Manuela Terrinoni; Natalie King-Lyons; Michael Lebens; Annabelle Varrot; Terry D Connell; Susann Teneberg
Journal:  Glycobiology       Date:  2022-04-21       Impact factor: 5.954

4.  Chemical and enzymatic transacylation of amide-linked FA of buttermilk gangliosides.

Authors:  Christopher Beermann; Anne-Katrin Röhrig; Günther Boehm
Journal:  Lipids       Date:  2003-08       Impact factor: 1.880

5.  Changes of the ganglioside pattern and content in human fibroblasts by high density cell population subculture progression.

Authors:  Mariateresa Sciannamblo; Vanna Chigorno; Alberto Passi; Rea Valaperta; Ileana Zucchi; Sandro Sonnino
Journal:  Glycoconj J       Date:  2002-03       Impact factor: 2.916

6.  A rapid method for the preparation of ganglioside Glac2 (GD3).

Authors:  R Jennemann; H Wiegandt
Journal:  Lipids       Date:  1994-05       Impact factor: 1.880

7.  Isolation and characterization of ganglioside 9-O-acetyl-GD3 from bovine buttermilk.

Authors:  D M Bonafede; L J Macala; M Constantine-Paton; R K Yu
Journal:  Lipids       Date:  1989-08       Impact factor: 1.880

8.  Apoptosis of human breast carcinoma cells in the presence of disialosyl gangliosides: II. Treatment of SKBR3 cells with GD3 and GD1b gangliosides.

Authors:  Rui Ma; Atanas Koulov; Christopher Moulton; Manju Basu; Sipra Banerjee; Holly Goodson; Subhash Basu
Journal:  Glycoconj J       Date:  2004       Impact factor: 3.009
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.