Literature DB >> 3969604

Bacterial inoculum and the activity of antimicrobial agents.

D E Fry, R N Garrison, L Trachtenberg, H C Polk.   

Abstract

Experimental and clinical infections have concentrations of bacteria that are greater than the concentrations used in the laboratory for the determination of in vitro activity. When realistic concentrations are used, the antibiotic activity is reduced. The optimum selection of antibiotics may require a re-examination of the laboratory procedures for the determination of sensitivity data.

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Year:  1985        PMID: 3969604

Source DB:  PubMed          Journal:  Surg Gynecol Obstet        ISSN: 0039-6087


  2 in total

1.  Synergistic effect of dosage and bacterial inoculum in TEM-1 mediated antibiotic resistance.

Authors:  J A Reguera; F Baquero; J C Perez-Diaz; J L Martinez
Journal:  Eur J Clin Microbiol Infect Dis       Date:  1988-12       Impact factor: 3.267

2.  Isolation, characterization, and mode of action on Escherichia coli strains of microcin D93.

Authors:  J L Martínez; J C Pérez-Díaz
Journal:  Antimicrob Agents Chemother       Date:  1986-03       Impact factor: 5.191

  2 in total

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