Literature DB >> 3957856

Dopamine-beta-hydroxylase (DBH) and homovanillic acid (HVA) in autistic children.

C Garnier, E Comoy, C Barthelemy, I Leddet, B Garreau, J P Muh, G Lelord.   

Abstract

In the present study, plasma DBH activity and urinary HVA levels were measured in 19 autistic and 15 normal children. DBH activity was significantly elevated in the 8 less retarded autistic patients. In this subgroup, a negative correlation was found between plasma DBH and urinary HVA levels. These results support the hypothesis of a possible involvement of brain catecholamine dysfunction in the production of autistic symptoms.

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Year:  1986        PMID： 3957856     DOI： 10.1007/bf01531575

Source DB:  PubMed          Journal:  J Autism Dev Disord        ISSN： 0162-3257


  21 in total

1.  A rapid and simple gas-liquid chromatographic procedure for homovanillic and vanillylmandelic acid in urine.

Authors:  M S Roginsky; R D Gordon; M J Bennett
Journal:  Clin Chim Acta       Date:  1974-11-08       Impact factor: 3.786

2.  Cerebrospinal fluid, plasma, and urinary MHPG in children.

Authors:  J G Young; D J Cohen; M E Kavanagh; H D Landis; B A Shaywitz; J W Maas
Journal:  Life Sci       Date:  1981-06-22       Impact factor: 5.037

3.  Decreased urinary free catecholamines in childhood autism.

Authors:  J G Young; D J Cohen; S L Brown; B K Caparulo
Journal:  J Am Acad Child Psychiatry       Date:  1978

4.  Contribution of plasma homovanillic acid (HVA) to urine and cerebrospinal fluid HVA in the monkey and its pharmacokinetic disposition.

Authors:  M A Elchisak; R J Polinsky; M H Ebert; K J Powers; I J Kopin
Journal:  Life Sci       Date:  1978-12-04       Impact factor: 5.037

5.  [Disturbances in dopamine metabolism in autistic children: results of clinical tests and urinary dosages of homovanilic acid (HVA)].

Authors:  B Garreau; C Barthelemy; J Domenech; D Sauvage; J P Muh; G Lelord; E Callaway
Journal:  Acta Psychiatr Belg       Date:  1980 May-Jun

6.  6-Hydroxydopamine lesions of dopaminergic A10 neurons. Long-term effects on the urinary excretion of free and conjugated catecholamines and their metabolites in the rat.

Authors:  L Peyrin; H Simon; J M Cottet-Emard; N Bruneau; M Le Moal
Journal:  Brain Res       Date:  1982-03-11       Impact factor: 3.252

Review 7.  NIH conference. Dopamine- -hydroxylase. Basic and clinical studies.

Authors:  I J Kopin; S Kaufman; H Viveros; D Jacobowitz; C R Lake; M G Ziegler; W Lovenberg; F K Goodwin
Journal:  Ann Intern Med       Date:  1976-08       Impact factor: 25.391

8.  [Modifications in urinary homovanillic acid after ingestion of vitamin B6; functional study in autistic children (author's transl)].

Authors:  G Lelord; E Callaway; J P Muh; J C Arlot; D Sauvage; B Garreau; J Domenech
Journal:  Rev Neurol (Paris)       Date:  1978-12       Impact factor: 2.607

9.  Gas chromatographic determination of urinary vanilglycolic acid, vanilglycol, vanilacetic acid and vanillactic acid-chemical parameters for the diagnosis of neurogenic tumours and the evaluation of their treatment.

Authors:  S K Wadman; D Ketting; P A Voûte
Journal:  Clin Chim Acta       Date:  1976-10-01       Impact factor: 3.786

10.  Decreased 24-hour urinary MHPG in childhood autism.

Authors:  J G Young; D J Cohen; B K Caparulo; S L Brown; J W Maas
Journal:  Am J Psychiatry       Date:  1979-08       Impact factor: 18.112
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  10 in total

1.  Plasma amino acid levels in children with autism and their families.

Authors:  Sarah Aldred; Kieran M Moore; Michael Fitzgerald; Rosemary H Waring
Journal:  J Autism Dev Disord       Date:  2003-02

2.  Investigation of whole blood and urine monoamines in autism.

Authors:  Josiane Hérault; Joëlle Martineau; Anne Perrot-Beaugerie; Jacqueline Jouve; Hervé Tournade; Catherine Barthelemy; Gilbert Lelord; Jean-Pierre Muh
Journal:  Eur Child Adolesc Psychiatry       Date:  1993-10       Impact factor: 4.785

3.  Childhood autism: An appeal for an integrative and psychobiological approach.

Authors:  Robert D Oades; Christian Eggers
Journal:  Eur Child Adolesc Psychiatry       Date:  1994-07       Impact factor: 4.785

4.  Growth hormone response to L-dopa and clonidine in autistic children.

Authors:  G M Realmuto; J B Jensen; E Reeve; B D Garfinkel
Journal:  J Autism Dev Disord       Date:  1990-12

Review 5.  Modeling dopamine dysfunction in autism spectrum disorder: From invertebrates to vertebrates.

Authors:  Gabriella E DiCarlo; Mark T Wallace
Journal:  Neurosci Biobehav Rev       Date:  2021-12-11       Impact factor: 8.989

6.  Catecholamines metabolism in infantile autism: a controlled study of 22 autistic children.

Authors:  J M Launay; C Bursztejn; P Ferrari; C Dreux; A Braconnier; E Zarifian; S Lancrenon; J Fermanian
Journal:  J Autism Dev Disord       Date:  1987-09

7.  Urinary free and conjugated catecholamines and metabolites in autistic children.

Authors:  C Barthelemy; N Bruneau; J M Cottet-Eymard; J Domenech-Jouve; B Garreau; G Lelord; J P Muh; L Peyrin
Journal:  J Autism Dev Disord       Date:  1988-12

8.  Etiology of autistic features: the persisting neurotoxic effects of propionic acid.

Authors:  Afaf K El-Ansary; Abir Ben Bacha; Malak Kotb
Journal:  J Neuroinflammation       Date:  2012-04-24       Impact factor: 8.322

9.  Association between 19-bp Insertion/Deletion Polymorphism of Dopamine β-Hydroxylase and Autism Spectrum Disorder in Thai Patients.

Authors:  Wikrom Wongpaiboonwattana; Areerat Hnoonual; Pornprot Limprasert
Journal:  Medicina (Kaunas)       Date:  2022-09-06       Impact factor: 2.948

10.  Gene expression profiling of lymphoblasts from autistic and nonaffected sib pairs: altered pathways in neuronal development and steroid biosynthesis.

Authors:  Valerie W Hu; AnhThu Nguyen; Kyung Soon Kim; Mara E Steinberg; Tewarit Sarachana; Michele A Scully; Steven J Soldin; Truong Luu; Norman H Lee
Journal:  PLoS One       Date:  2009-06-03       Impact factor: 3.240
  10 in total

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