| Literature DB >> 3957003 |
G M Lathrop, J M Lalouel, R L White.
Abstract
Methods are given for efficient calculation of the likelihood for multilocus linkage in families comprised of grandparents, parents, and children. Such families are being used in large-scale cooperative efforts to build a detailed linkage map of the human genome. The methods are illustrated by an application to loci on chromosome 13.Entities:
Mesh:
Year: 1986 PMID: 3957003 DOI: 10.1002/gepi.1370030105
Source DB: PubMed Journal: Genet Epidemiol ISSN: 0741-0395 Impact factor: 2.135