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Literature DB >> 3954730

Trans-stimulation and trans-inhibition of uridine efflux from human erythrocytes by permeant nucleosides.

Abstract

The ability of nucleoside permeants to accelerate the efflux of uridine from human erythrocytes has been compared. In contrast to uridine, 2-chloroadenosine acted as a trans-inhibitor of uridine efflux from fresh human erythrocytes, and adenosine had little effect. These results are consistent with the lower maximum velocity for influx of 2-chloroadenosine and adenosine as compared with uridine and demonstrate that trans acceleration experiments do not discriminate between transported and non-transported permeants for the human erythrocyte nucleoside carrier.

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Year: 1986 PMID： 3954730 PMCID： PMC1153021 DOI： 10.1042/bj2330295

Source DB: PubMed Journal: Biochem J ISSN： 0264-6021 Impact factor: 3.857

11 in total

1. Mediated transport of nucleosides in human erythrocytes. Accelerative exchange diffusion of uridine and thymidine and specificity toward pyrimidine nucleosides as permeants.

Authors: C E Cass; A R Paterson
Journal: J Biol Chem Date: 1972-05-25 Impact factor: 5.157

2. Nucleoside transport. I. A mediated process in human erythrocytes.

Authors: J M Oliver; A R Paterson
Journal: Can J Biochem Date: 1971-02

3. Transport of uridine in human red blood cells. Demonstration of a simple carrier-mediated process.

Authors: Z I Cabantchik; H Ginsburg
Journal: J Gen Physiol Date: 1977-01 Impact factor: 4.086

Review 4. Nucleoside transport in animal cells.

Authors: J D Young; S M Jarvis
Journal: Biosci Rep Date: 1983-04 Impact factor: 3.840

5. Inward fluxes of adenosine in erythrocytes and cultured cells measured by a quenched-flow method.

Authors: A R Paterson; E R Harley; C E Cass
Journal: Biochem J Date: 1984-12-15 Impact factor: 3.857

6. Azomycin riboside, a sugar homologue of misonidazole with favorable radiosensitizing properties.

Authors: S M Jarvis; J D Chapman; J Ngan-Lee; K A Rutledge; P J Barr; A R Paterson
Journal: Cancer Res Date: 1982-11 Impact factor: 12.701

7. Nucleoside transport in human and sheep erythrocytes. Evidence that nitrobenzylthioinosine binds specifically to functional nucleoside-transport sites.

Authors: S M Jarvis; J D Young
Journal: Biochem J Date: 1980-08-15 Impact factor: 3.857

8. Inhibition of adenosine uptake in human erythrocytes by adenosine-5'-carboxamides, xylosyladenine, dipyridamole, hexobendine, and p-nitrobenzylthioguanosine.

Authors: K Turnheim; B Plank; N Kolassa
Journal: Biochem Pharmacol Date: 1978 Impact factor: 5.858

9. Nucleoside transport in human erythrocytes. A simple carrier with directional symmetry in fresh cells, but with directional asymmetry in cells from outdated blood.

Authors: S M Jarvis; J R Hammond; A R Paterson; A S Clanachan
Journal: Biochem J Date: 1983-02-15 Impact factor: 3.857

3. Effects of phorbol, dexamethasone and starvation on 3-O-methyl-D-glucose transport by rat thymocytes. Modulation of transport by altered trans effects.

Authors: R J Naftalin; R J Rist
Journal: Biochem J Date: 1990-01-01 Impact factor: 3.857

3 in total