Literature DB >> 3953723

Cyclosporine eyedrops for the treatment of severe vernal keratoconjunctivitis.

D BenEzra, J Pe'er, M Brodsky, E Cohen.   

Abstract

Twelve children with severe chronic vernal keratoconjunctivitis participated in a pilot study aimed at evaluating the effect of 2% cyclosporine eyedrops on the clinical course and symptoms of this disease. Eleven of the 12 children showed improvement after the first week of treatment. Nine patients demonstrated persistent improvement at the completion of the treatment schedule after six weeks. However, although seven of the children were symptom-free while being treated, only three were free of disease two months after cessation of the cyclosporine eyedrops. The other nine showed rapid recurrence of their symptoms.

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Year:  1986        PMID: 3953723     DOI: 10.1016/0002-9394(86)90819-6

Source DB:  PubMed          Journal:  Am J Ophthalmol        ISSN: 0002-9394            Impact factor:   5.258


  19 in total

Review 1.  Ocular allergy treatments.

Authors:  L Bielory
Journal:  Clin Rev Allergy Immunol       Date:  2001-04       Impact factor: 8.667

2.  Systemic cyclosporin A in high failure risk, repeated corneal transplantation.

Authors:  S Rumelt; V Bersudsky; T Blum-Hareuveni; U Rehany
Journal:  Br J Ophthalmol       Date:  2002-09       Impact factor: 4.638

Review 3.  Emerging indications for the use of cyclosporin in organ transplantation and autoimmunity.

Authors:  P A Keown
Journal:  Drugs       Date:  1990-09       Impact factor: 9.546

4.  Vernal keratoconjunctivitis in school children in Rwanda and its association with socio-economic status: a population-based survey.

Authors:  Stefan De Smedt; John Nkurikiye; Yannick Fonteyne; Arjan Hogewoning; Marjan Van Esbroeck; Dirk De Bacquer; Stephen Tuft; Clare Gilbert; Joris Delanghe; Philippe Kestelyn
Journal:  Am J Trop Med Hyg       Date:  2011-10       Impact factor: 2.345

5.  Topical treatment of severe corneal ulcers with cyclosporin A.

Authors:  M Zierhut; H J Thiel; E G Weidle; R Waetjen; U Pleyer
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  1989       Impact factor: 3.117

6.  Resection and cryotherapy combined with amniotic membrane transplantation for the treatment of vernal keratoconjunctivitis with giant papillae.

Authors:  Dongling Jiang; Mingchang Zhang; Yanhua Hu
Journal:  J Huazhong Univ Sci Technolog Med Sci       Date:  2006

Review 7.  Topical ciclosporin in the treatment of ocular surface disorders.

Authors:  S Tatlipinar; E K Akpek
Journal:  Br J Ophthalmol       Date:  2005-10       Impact factor: 4.638

Review 8.  Cyclosporin. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use in immunoregulatory disorders.

Authors:  Diana Faulds; Karen L Goa; Paul Benfield
Journal:  Drugs       Date:  1993-06       Impact factor: 9.546

Review 9.  Therapeutic options in ocular allergic disease.

Authors:  M Hingorani; S Lightman
Journal:  Drugs       Date:  1995-08       Impact factor: 9.546

Review 10.  [Ocular involvement in atopic dermatitis : Clinical aspects and therapy].

Authors:  P Maier; T Lapp; T Reinhard
Journal:  Ophthalmologe       Date:  2017-06       Impact factor: 1.059

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