Literature DB >> 3953648

Speech disturbances (cluttering) in mildly impaired males with the Martin-Bell/fragile X syndrome.

D M Hanson, A W Jackson, R J Hagerman.   

Abstract

The language characteristics of fra(X) males (n = 10) with an IQ greater than or equal to 70 were evaluated. Language testing demonstrated relatively stronger receptive vocabulary skills compared to weak auditory memory and processing skills. A characteristic speech and language disturbance, cluttering, was present in 9 of the 10 study patients. Their speech was characterized by a fast and fluctuating rate of speech, and repetitions of sounds, words or phrases. Other aspects of cluttering including attentional problems, hyperactivity, motor delays and reading difficulties are commonly seen in the fra(X) syndrome. Cluttering may be helpful in identifying the fra(X) syndrome in a male who is not retarded.

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Year:  1986        PMID: 3953648     DOI: 10.1002/ajmg.1320230114

Source DB:  PubMed          Journal:  Am J Med Genet        ISSN: 0148-7299


  20 in total

1.  A comparison of pragmatic language in boys with autism and fragile X syndrome.

Authors:  Jessica Klusek; Gary E Martin; Molly Losh
Journal:  J Speech Lang Hear Res       Date:  2014-10       Impact factor: 2.297

2.  Parental inheritance and psychological disability in fragile X females.

Authors:  A L Reiss; L Freund; S Vinogradov; R Hagerman; A Cronister
Journal:  Am J Hum Genet       Date:  1989-11       Impact factor: 11.025

Review 3.  Language phenotypes and intervention planning: bridging research and practice.

Authors:  Deborah J Fidler; Amy Philofsky; Susan L Hepburn
Journal:  Ment Retard Dev Disabil Res Rev       Date:  2007

4.  Direct magnitude estimation of articulation rate in boys with fragile X syndrome.

Authors:  David J Zajac; Adrianne A Harris; Joanne E Roberts; Gary E Martin
Journal:  J Speech Lang Hear Res       Date:  2009-08-28       Impact factor: 2.297

Review 5.  Potassium channel modulation and auditory processing.

Authors:  Maile R Brown; Leonard K Kaczmarek
Journal:  Hear Res       Date:  2011-03-21       Impact factor: 3.208

6.  Fragile X syndrome in autistic boys.

Authors:  H H Ho; D K Kalousek
Journal:  J Autism Dev Disord       Date:  1989-06

7.  Fragile X mental retardation protein is required for rapid experience-dependent regulation of the potassium channel Kv3.1b.

Authors:  John G Strumbos; Maile R Brown; Jack Kronengold; Daniel B Polley; Leonard K Kaczmarek
Journal:  J Neurosci       Date:  2010-08-04       Impact factor: 6.167

8.  A Retrospective Video Analysis of Canonical Babbling and Volubility in Infants with Fragile X Syndrome at 9-12 Months of Age.

Authors:  Katie Belardi; Linda R Watson; Richard A Faldowski; Heather Hazlett; Elizabeth Crais; Grace T Baranek; Cara McComish; Elena Patten; D Kimbrough Oller
Journal:  J Autism Dev Disord       Date:  2017-04

9.  Perseveration in the connected speech of boys with Fragile X syndrome with and without autism spectrum disorder.

Authors:  Gary E Martin; Joanne E Roberts; Nancy Helm-Estabrooks; John Sideris; Jacqueline Vanderbilt; Lauren Moskowitz
Journal:  Am J Intellect Dev Disabil       Date:  2012-09

10.  The neural basis of auditory temporal discrimination in girls with fragile X syndrome.

Authors:  Scott S Hall; Elizabeth Walter; Elena Sherman; Fumiko Hoeft; Allan L Reiss
Journal:  J Neurodev Disord       Date:  2009-03       Impact factor: 4.025

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