Literature DB >> 3950668

Multiple sclerosis: failure of treatment with verapamil in a pilot trial.

S Komoly, G Jakab, A Fazekas.   

Abstract

Verapamil hydrochloride, a lipophilic calcium channel blocking agent was used in the treatment of 11 patients with multiple sclerosis. The rationale of the therapy was to improve the conduction capacity of the damaged nerve fibres. The therapy did not prove effective in a pilot trial.

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Year:  1986        PMID： 3950668     DOI： 10.1007/bf00313996

Source DB:  PubMed          Journal:  J Neurol        ISSN： 0340-5354            Impact factor:   4.849


  17 in total

1.  The pathophysiology of demyelination and its implications for the symptomatic treatment of multiple sclerosis.

Authors:  T A Sears; H Bostock; M Sheratt
Journal:  Neurology       Date:  1978-09       Impact factor: 9.910

2.  A working protocol to be used as a guideline for trials in multiple sclerosis.

Authors:  H L Weiner; G W Ellison
Journal:  Arch Neurol       Date:  1983-10-21

Review 3.  Adverse reactions to calcium antagonists.

Authors:  J G Lewis
Journal:  Drugs       Date:  1983-02       Impact factor: 9.546

4.  Evoked potentials in the diagnosis of multiple sclerosis: a follow up study.

Authors:  W B Matthews; J R Wattam-Bell; E Pountney
Journal:  J Neurol Neurosurg Psychiatry       Date:  1982-04       Impact factor: 10.154

5.  Brain-stem involvement in multiple sclerosis: a comparison between brain-stem auditory evoked potentials and the acoustic stapedius reflex.

Authors:  B Kofler; G Oberascher; B Pommer
Journal:  J Neurol       Date:  1984       Impact factor: 4.849

6.  The hot bath test in the diagnosis of multiple sclerosis.

Authors:  A S Malhotra; H Goren
Journal:  JAMA       Date:  1981-09-04       Impact factor: 56.272

7.  Exacerbations, activity, and progression in multiple sclerosis.

Authors:  C M Poser
Journal:  Arch Neurol       Date:  1980-08

8.  [On the temperature sensitivity of multiple sclerosis patients (author's transl)].

Authors:  M Brenneis; G Harrer; H Selzer
Journal:  Fortschr Neurol Psychiatr Grenzgeb       Date:  1979-06

9.  Forms of benign multiple sclerosis. Report of two "clinically silent" cases discovered at autopsy.

Authors:  R P Mackay; A Hirano
Journal:  Arch Neurol       Date:  1967-12

10.  Cranial computed tomography in the diagnosis of multiple sclerosis.

Authors:  L A Loizou; E B Rolfe; H Hewazy
Journal:  J Neurol Neurosurg Psychiatry       Date:  1982-10       Impact factor: 10.154
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