Literature DB >> 3950641

Elevated levels of free putrescine and N1-acetylspermidine in cyst fluids of malignant brain tumours.

H Yamazaki, T Tsukahara, J Uki, S Matsuzaki.   

Abstract

The contents of free and conjugated polyamines in cyst fluids of brain tumours were analysed. The putrescine and N1-acetylspermidine levels in cyst fluids of malignant brain tumours were significantly higher than those of benign tumours. The free spermidine levels in malignant and benign tumours were about the same, while the total spermidine levels were higher in malignant than those in benign tumours. These results suggest that polyamine levels in cyst fluids reflect the altered polyamine metabolism in brain tumours.

Entities:  

Mesh:

Substances:

Year:  1986        PMID: 3950641      PMCID: PMC1028691          DOI: 10.1136/jnnp.49.2.209

Source DB:  PubMed          Journal:  J Neurol Neurosurg Psychiatry        ISSN: 0022-3050            Impact factor:   10.154


  8 in total

Review 1.  Polyamines in rapid growth and cancer.

Authors:  J Jänne; H Pösö; A Raina
Journal:  Biochim Biophys Acta       Date:  1978-04-06

Review 2.  Polyamines in mammalian tumors. Part II.

Authors:  G Scalabrino; M E Ferioli
Journal:  Adv Cancer Res       Date:  1982       Impact factor: 6.242

3.  Polyamine conjugates and total polyamine concentrations in human amniotic fluid.

Authors:  W Y Chan; T W Seale; J B Shukla; O M Rennert
Journal:  Clin Chim Acta       Date:  1979-02-01       Impact factor: 3.786

4.  Selective elevation of the N1-acetylspermidine level in human colorectal adenocarcinomas.

Authors:  S Takenoshita; S Matsuzaki; G Nakano; H Kimura; H Hoshi; H Shoda; T Nakamura
Journal:  Cancer Res       Date:  1984-02       Impact factor: 12.701

Review 5.  Biochemical markers of central nervous system tumors measured in cerebrospinal fluid and their potential use in diagnosis and patient management: a review.

Authors:  J Seidenfeld; L J Marton
Journal:  J Natl Cancer Inst       Date:  1979-10       Impact factor: 13.506

6.  Polyamine metabolism III: urinary acetyl polyamines in human cancer.

Authors:  M M Abdel-Monem; K Ohno
Journal:  J Pharm Sci       Date:  1978-12       Impact factor: 3.534

7.  CSF polyamines: a new and important means of monitoring patients with medulloblastoma.

Authors:  L J Marton; M S Edwards; V A Levin; W P Lubich; C B Wilson
Journal:  Cancer       Date:  1981-02-15       Impact factor: 6.860

8.  Enhanced urinary excretion of N1-acetylspermidine and the presence of tumors.

Authors:  N Seiler; A Graham; J Bartholeyns
Journal:  Cancer Res       Date:  1981-04       Impact factor: 12.701

  8 in total
  1 in total

1.  The additive effect of alpha-difluoromethylornithine (DFMO) and radiation therapy on a rat glioma model.

Authors:  T Tsukahara; M Tamura; H Yamazaki; H Kurihara; S Matsuzaki
Journal:  J Cancer Res Clin Oncol       Date:  1992       Impact factor: 4.553

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.