Literature DB >> 394730

A protease-antiprotease system in antrochoanal polyp. I. Evidence for the existence of proactivator.

T Kosugi, T Morimitsu, O Matsuo, H Mihara.   

Abstract

Tissue extract of antrochoanal polyps showed a faint lysis area on standard fibrin plates, but streptokinase (SK)-added tissue extract showed a large lysis area. No fibrinolytic activity was observed on plasminogen-free fibrin plates. It is concluded, therefore, that the fibrinolytic activity observed after SK addition is indicative of the existence of SK-responsive protein proactivator. The tissue extract did not contain plasminogen or antiprotease against trypsin or papain. It was stable at neutral pH at 37 degrees C and stable at acid pH at 70 degrees C. The role of proactivator is discussed in relation to the growth or enlargement of antrochoanal polyps.

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Year:  1979        PMID： 394730     DOI： 10.1007/bf00455209

Source DB:  PubMed          Journal:  Arch Otorhinolaryngol        ISSN： 0302-9530


  14 in total

1.  STUDIES ON THE FIBRINOLYSIS IN TUMOR BEARING MICE. II. APPEARANCE OF FIBRINOLYTIC ENZYME IN ASCITES AFTER TUMOR CELLS INOCULATION.

Authors:  K KINJO; H MIHARA; Y FUNAHARA
Journal:  Kobe J Med Sci       Date:  1963-12

2.  FRACTIONATION OF PLASMINOGEN ACTIVATOR AND PROACTIVATOR IN TISSUE AND BLOOD BY GEL FILTRATION.

Authors:  A TAKADA; Y TAKADA; U OKAMOTO
Journal:  Keio J Med       Date:  1964-12

3.  GEL FILTRATION OF FIBRINOLYTIC COMPONENTS OF BLOOD PLASMA IN MAN AND RABBIT.

Authors:  A TAKADA; Y TAKADA; U OKAMOTO
Journal:  Keio J Med       Date:  1965-03

4.  Isolation of material with proactivator activity from human serum.

Authors:  H B GREIG; E M CORNELIUS
Journal:  Nature       Date:  1960-09-24       Impact factor: 49.962

5.  Fibrinolytic activity in some human body fluids.

Authors:  O K ALBRECHTSEN; O STORM; M CLAASSEN
Journal:  Scand J Clin Lab Invest       Date:  1958       Impact factor: 1.713

6.  The fibrin plate method for estimating fibrinolytic activity.

Authors:  T ASTRUP; S MULLERTZ
Journal:  Arch Biochem Biophys       Date:  1952-10       Impact factor: 4.013

7.  The electrophoretic analysis of the "nasal fibrinolytic enzyme".

Authors:  Y Sasaki
Journal:  Acta Otolaryngol       Date:  1968-04       Impact factor: 1.494

8.  [Studies on a plasminogen activating system in human milk. I. Isolation of plasminogen activator and proactivator from human milk, and estimation of their molecular weights (author's transl)].

Authors:  U Okamoto; Y Nagamatsu; M Matsumoto; J Yamamoto
Journal:  Nihon Ketsueki Gakkai Zasshi       Date:  1974-04

9.  Studies on the fibrinolysis in tumor bearing mice. 3. Demonstration of the plasminogen activator in Ehrlich ascites tumor cells.

Authors:  Y Funahara; H Mihara; K Kinjo
Journal:  Kobe J Med Sci       Date:  1965-06

10.  Plasminogen activator from human embryonic kidney cell cultures. Evidence for a proactivator.

Authors:  C Nolan; L S Hall; G H Barlow; I I Tribby
Journal:  Biochim Biophys Acta       Date:  1977-02-28
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  1 in total

1.  Is There any Possible Role of Neurotrophin 3 in the Pathogenesis of Antrochoanal Polyp?

Authors:  Cengiz Ozcan; Onur Ismi; Tuba Kara; Gurbuz Polat; Osman Erdogan; Senay Balci Fidanci; Yusuf Vayisoglu; Kemal Gorur
Journal:  Medeni Med J       Date:  2020-02-28
  1 in total

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